hCAI/II-IN-1 | whatman (沃特曼)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

hCAI/II-IN-1

hCAI/II-IN-1 (Compound 3h) 是一种人碳酸酐酶 I 和 II (hCA I/II) 抑制剂，对 hCA I 和 hCA II 的 IC₅₀ 值分别为 0.047 µM 和 0.024 µM。

hCAI/II-IN-1 Chemical Structure

CAS No. : 2422028-82-6

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生物活性	hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor with IC₅₀ values of 0.047 µM and 0.024 µM against hCA I and hCA II, respectively^[1].
IC₅₀ & Target	IC₅₀: 0.024 µM (hCA II), 0.047 µM (hCA I)^[1] K_i: 0.013 µM (hCA II), 0.032 µM (hCA I)^[1]
分子量	459.65
Formula	C₁₈H₂₉N₅O₃S₃
CAS 号	2422028-82-6
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Sağlık BN, et al. Synthesis, characterization and carbonic anhydrase I and II inhibitory evaluation of new sulfonamide derivatives bearing dithiocarbamate. Eur J Med Chem. 2020 Jul 15;198:112392.

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