PDHK-IN-4 | whatman (沃特曼)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

PDHK-IN-4

PDHK-IN-4 (Compound 30) 是一种有效的 PDHK 抑制剂，对 PDHK2 和 PDHK4 的 IC₅₀s 分别为 0.0051 和 0.0122 μM。丙酮酸脱氢酶激酶 (PDHK) 是许多疾病（包括糖尿病和癌症）的迷人药物靶点。PDHK-IN-4 具有研究癌症疾病的潜力。

PDHK-IN-4 Chemical Structure

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

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生物活性	PDHK-IN-4 (Compound 30) is a potent inhibitor of PDHK with IC₅₀s of 0.0051 and 0.0122 μM for PDHK2 and PDHK4, repectively. Pyruvate dehydrogenase kinases (PDHKs) are fascinating drug targets for numerous diseases, including diabetes and cancers. PDHK-IN-4 has the potential for the research of cancer diseases^[1].
分子量	431.49
Formula	C₂₄H₂₅N₅O₃
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Bessho Y, et al. Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitors. Bioorg Med Chem. 2021 Dec 15;52:116514

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