HBV-IN-23

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

HBV-IN-23 

HBV-IN-23 (Compound 5k) 是一种 HBV DNA 复制抑制剂，IC50 值为 0.58 µM。HBV-IN-23 在药物敏感和耐药株中均有抑制作用。HBV-IN-23 具有抗肝癌细胞 (HCC) 活性，诱导 HepG2 细胞凋亡。

HBV-IN-23

HBV-IN-23 Chemical Structure

CAS No. : 2413649-89-3

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

HBV-IN-23 (Compound 5k) is an inhibitor of HBV DNA replication with an IC50 of 0.58 µM. HBV-IN-23 inhibits HBV DNA replication in both drug sensitive and resistant HBV strains. HBV-IN-23 shows anti-hepatocellular carcinoma cell (HCC) activities. HBV-IN-23 induces HepG2 cells apoptosis[1].

IC50 & Target

IC50: 0.58 µM (HBV DNA replication)[1]
分子量

449.57

Formula

C25H27N3O3S
CAS 号

2413649-89-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Qiu J, et al. Discovery of novel quinazolinone derivatives as potential anti-HBV and anti-HCC agents. Eur J Med Chem. 2020 Nov 1;205:112581.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务