DNA crosslinker 3 dihydrochloride

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DNA crosslinker 3 dihydrochloride 

DNA crosslinker 3 (dihydrochloride) (compound 1) 是一种 DNA 小沟结合剂，与 DNA 的结合亲和力 (ΔTm) 为 1.4 °C。DNA crosslinker 3 (dihydrochloride) 可用于抗癌研究。

DNA crosslinker 3 dihydrochloride

DNA crosslinker 3 dihydrochloride Chemical Structure

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生物活性

DNA crosslinker 3 (dihydrochloride) (compound 1) is a potent DNA minor groove binder with DNA binding affinity (ΔTm) of 1.4 °C. DNA crosslinker 3 (dihydrochloride) can be used for researching anticancer[1].

IC50 & Target

DNA[1]
分子量

401.29

Formula

C15H22Cl2N8O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Costas-Lago MC, et al. Novel Pyridazin-3(2H)-one-Based Guanidine Derivatives as Potential DNA Minor Groove Binders with Anticancer Activity. ACS Med Chem Lett. 2022;13(3):463-469. Published 2022 Feb 10.

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