CD73-IN-11

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

CD73-IN-11 

CD73-IN-11 是一种有效的 CD73 抑制剂。CD73 可以催化细胞外5′-磷酸腺苷 (5′-AMP) 产生腺苷,腺苷可以诱导免疫抑制作用,促进肿瘤增殖和/或转移。CD73-IN-11 用于制备治疗肿瘤相关疾病的药物 (摘自专利 WO2022068929A1,化合物 24)。

CD73-IN-11

CD73-IN-11 Chemical Structure

CAS No. : 2766566-11-2

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生物活性

CD73-IN-11 is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5′-phosphate adenosine (5′-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-11 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022068929A1, compound 24)[1].

分子量

337.26

Formula

C14H10F3N5O2

CAS 号

2766566-11-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Xuejun Zhang, et al. Pyrimidinedione compound and use thereof. Patent WO2022068929A1.

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