Anticancer agent 52

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Anticancer agent 52 

Anticancer agent 52 是一种有效的抗癌剂。Anticancer agent 52 显示出体外细胞毒性。Anticancer agent 52 诱导细胞凋亡 (apoptosis)。Anticancer agent 52 显示出抗肿瘤作用。Anticancer agent 52 具有研究膀胱癌的潜力。

Anticancer agent 52

Anticancer agent 52 Chemical Structure

CAS No. : 2388983-64-8

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生物活性

Anticancer agent 52 is a potent anticancer agent. Anticancer agent 52 shows in vitro cytotoxicity. Anticancer agent 52 induces apoptosis. Anticancer agent 52 shows antitumor effect. Anticancer agent 52 has the potential for the research of bladder cancer[1].

体外研究
(In Vitro)

Anticancer agent 52 (compound TPP1) (0-2048 µM) shows cytotoxicity with IC50s of 200, 200, 150, 200, 240, 80 µM for 5637, RT112, RT4, SWT80, TCCSUP, UMUC3 cells, respectively[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis[1]

Cell Line: RT112 cells
Concentration: 200 µM
Incubation Time: 1, 2, 4 h
Result: Induced apoptosis with the increased the expression of c-PARP.

分子量

862.67

Formula

C50H43Br2N2P
CAS 号

2388983-64-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Stromyer ML, et al. Synthesis, characterization, and biological activity of a triphenylphosphonium-containing imidazolium salt against select bladder cancer cell lines. Eur J Med Chem. 2020 Jan 1;185:111832.

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