hDHODH-IN-9

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

hDHODH-IN-9 

hDHODH-IN-9 (Compound 3k) 是一种有效的 hDHODH 抑制剂，IC50 为 0.34 μM。hDHODH-IN-9 表现出对 MCF-7 和 A375 细胞的高细胞毒活性和良好的选择性。hDHODH-IN-9 具有研究癌症疾病的潜力。

hDHODH-IN-9

hDHODH-IN-9 Chemical Structure

CAS No. : 133676-47-8

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生物活性

hDHODH-IN-9 (Compound 3k) is a potent inhibitor of hDHODH with an IC50 of 0.34 μM. hDHODH-IN-9 demonstrates high cytotoxic activity against MCF-7 and A375 cells and good selectivity. hDHODH-IN-9 has the potential for the research of cancer diseases[1].

分子量

351.40

Formula

C21H21NO4
CAS 号

133676-47-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Petrović MM, et al. Potent human dihydroorotate dehydrogenase inhibitory activity of new quinoline-4-carboxylic acids derived from phenolic aldehydes: Synthesis, cytotoxicity, lipophilicity and molecular docking studies. Bioorg Chem. 2020;105:104373.

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