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Niclosamide sodium (Synonyms: BAY2353 sodium)
Niclosamide (BAY2353) sodium 是一种具有口服活性的用于寄生虫感染研究的抗蠕虫化合物。
Niclosamide sodium 是 STAT3 抑制剂,在 HeLa 细胞中的 IC50 为 0.25 μM。
Niclosamide sodium 具有抗癌的生物活性,并能抑制 Vero E6 细胞的 DNA 复制。
Niclosamide sodium Chemical Structure
CAS No. : 40321-86-6
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Niclosamide sodium 的其他形式现货产品:
生物活性 |
Niclosamide (BAY2353) sodium is an orally active antihelminthic agent used in parasitic infection research[1].Niclosamide sodium is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells[4].Niclosamide sodium has biological activities against cancer, and inhibits DNA replication in Vero E6 cells[2][3][5]. |
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体外研究 (In Vitro) |
Niclosamide sodium (0.6 nM-46 µM) treatment inhibits adrenocortical carcinoma cellular proliferation in BD140A, SW-13, and NCI-H295R cells[3]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay[3]
Cell Viability Assay[4]
Western Blot Analysis[5]
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体内研究 (In Vivo) |
Niclosamide sodium (oral gavage; 100 mg/kg, 200 mg/kg; once a week; 8 weeks) treatment inhibits adrenocortical carcinoma tumor growth in vivo[3]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
349.10 |
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Formula |
C13H7Cl2N2NaO4 |
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CAS 号 |
40321-86-6 |
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中文名称 |
氯硝柳胺钠 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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