| 名称 |
(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-675) |
| 编码 |
[150234-52-9] |
| 别名 |
(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-675) |
| 纯度 |
80%，90%，95%，98%，99% |
| 重量 |
1mg,5mg,10mg,50mg,100mg,1g |
| 序列（单字母缩写） |
SEVNLDAEF |
| 序列（三字母缩写） |
H-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-OH (trifluoroacetate salt) |
| 基本描述 |
This peptide comprises a Cu2+-binding site. Binding of Cu2+ to the peptide induced oxidation of the cysteine and intermolecular dimerization of the peptide. The reduction of Cu2+ to Cu+ by Amyloid beta/A4 Protein Precursor may enhance the production of hydroxyl radicals which in turn may contribute to neurodegeneration in Alzheimer’s disease. |
| 溶解度 |
|
| 分子量 |
1023.1 |
| 化学式 |
C44H66N10O18 |
| 存储条件 |
Store at -20°C. Keep tightly closed. Store in a cool dry place. |
| 注释 |
|
| Documents |
![(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-675) 编码 [150234-52-9]](http://www.fluoroprobe.com/wp-content/uploads/2022/10/20221006_633e5b548c029.png) |
| Figures |
![(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-675) 编码 [150234-52-9]](http://www.fluoroprobe.com/wp-content/uploads/2022/10/20221006_633e5b54dfe07.jpg) |
| Reference |
M. Citron et al., Nature, 360, 672 (1992) M. Mullan et al., Nature Gen., 1, 345 (1992) S.R. Sahasrabudhe et al., J. Biol. Chem., 268, 16699 (1993) |
| C端 |
|
| N端 |
|
| 化学桥 |
|
