D-青霉胺
铜螯合剂。半胱氨酸的结构类似物。
10mM in Water
有货
基本信息
| 产品名称 | D-青霉胺 |
|---|---|
| 英文名称 | D-Penicillamine |
| 别名 | D-(-)-青霉胺 |
| 英文别名 | Cuprimine; 3-Mercapto-D-valine; Mercaptovaline; Penicillamine; D-β,β-Dimethylcysteine; D-()-2-Amino-3-mercapto-3-methylbutanoic acid; D-β-Mercaptovaline;3,3-Dimethyl-D-cysteine |
| 规格或纯度 | 10mM in Water |
| 运输条件 | 超低温冰袋运输 |
| 生化机理 | Penicillamine is a characteristic degradation product of penicillin type antibiotics. One atom of copper combines with two molecules of penicillamine. Penicillamine reduces excess cystine excretion in cystinuria. This is by disulfide interchange between penicillamine and cystine, which results in formation of a readily excreted penicillamine-cysteine disulfide. Penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. Penicillamine lowers IgM rheumatoid factor and depresses T-cell activity.Copper chelator. Structural analog of cysteine and metabolite of penicillin. Displays a variety of biological effects. Acts as an immunosuppressant and shows antirheumatic effect. Active in vivo . |
一般描述
Penicillamine is an exogenous NOS modulator, found to inhibit urease activity.
Penicillamine is an exogenous NOS modulator, found to inhibit urease activity.
It is used as an antirheumatic and as a chelating agent in Wilson′s disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding and to inhibit the growth of asynchronous cultures of rabbit articular chondrocytes.
相关属性
| CAS编号 | 52-67-5 |
|---|---|
| 敏感性 | 对热敏感 |
| 比旋光度 | -63o |
| 折光率 | 1.53 |
| 熔点 | 210°C |
| 沸点 | 251.8° C |
| 储存温度 | -80℃储存 |
| Reaxys-RN | 1722375 |
| RTECS | YV9425000 |
| 分子量 | 149.21 |
| 分子式 | C5H11NO2S |
| EC号 | 200-148-8 |
| 品牌 | Jinpan |
| PubChem CID | 5852 |