Fmoc-L-Leu-OSu
Fmoc保护的亮氨酸衍生物
有货
基本信息
产品名称 | Fmoc-L-Leu-OSu |
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英文名称 | Fmoc-L-Leu-OSu |
英文别名 | 2,5-Dioxopyrrolidin-1-yl N-[(9H-fluoren-9-ylmethoxy)carbonyl]leucinate |
运输条件 | 冰袋运输 |
一般描述
Fmoc-L-Leu-OSu是Fmoc保护的亮氨酸衍生物,可能对蛋白质组学研究和固相肽合成技术有用。亮氨酸是较简单的氨基酸之一-异丁基作为侧链。当掺入多肽链时,该较小的侧链赋予高度的柔性,并赋予中等的疏水作用。通常用诸如吡啶之类的碱除去Fmoc基团-这是酸性labile Boc基团的正交脱保护策略。
Fmoc-L-Leu-OSu is an Fmoc protected leucine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Leucine is one of the more simple amino acids – an isobutyl group as the side chain. This smaller side chain confers a high degree of flexibility, and imparts a moderate hydrophobic effect when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine – an orthogonal de-protection strategy to the acid labilie Boc group.
相关属性
CAS编号 | 76542-83-1 |
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熔点 | 120-125° C |
储存温度 | 2-8°C储存 |
分子量 | 450.5 |
分子式 | C25H26N2O6 |
品牌 | Jinpan |
Smiles | 2,5-Dioxopyrrolidin-1-yl N-[(9H-fluoren-9-ylmethoxy)carbonyl]leucinate |
PubChem CID | 51340597 |