Fmoc-3-碘-D-酪氨酸

Fmoc-3-碘-D-酪氨酸是Fmoc保护的酪氨酸衍生物，在蛋白质组学研究和固相多肽合成技术中具有潜在的应用价值。酪氨酸是一种非常重要的氨基酸，是为数不多的磷酸化以改变肽的物理性质的氨基酸之一，也是形成碘化甲状腺激素的前体。Fmoc基团通常用吡啶之类的碱除去，这是一种与抗酸Boc基团正交的去保护策略。

Fmoc-3-iodo-D-tyrosine is an Fmoc protected tyrosine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Tyrosine is a very important amino acid – one of the few amino acids which is phosphorylated to vary the physical properties of the peptides, and is a precursor for the formation of iodinated thyroid hormones. The Fmoc group is typically removed with a base such as pyridine – an orthogonal de-protection strategy to the acid labilie Boc group.