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名称 | Pannexin-1 (Panx1), Mimetic Blocking Pepti |
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别名 | Pannexin-1 (Panx1), Mimetic Blocking Pepti |
纯度 | 80%,90%,95%,98%,99% |
重量 | 1mg,5mg,10mg,50mg,100mg,1g |
序列(单字母缩写) | WRQAAFVDSY |
序列(三字母缩写) | H-Trp-Arg-Gln-Ala-Ala-Phe-Val-Asp-Ser-Tyr-OH (trifluoroacetate salt) |
基本描述 | This is amino acids 796 to 815 fragment of the chicken gizzard smooth-muscle myosin light-chain kinase (smMLCKp or P7) peptide, calmodulin (CaM)-binding domain . It retains its affinity for CaM and represents an adequate model for a complex of CaM with intact smMLCK protein. In the globular (Ca2+)4-CaM-P7 complex, the protein is wrapped around the -helical peptide. All the lysine and arginine charges of P7 are in close contact with the negatively charged side chains of the acidic residues of CaM. Calmodulin operates as a Ca2+ sensor and is known to interact with and regulate hundreds of proteins involved in many aspects of cellular function. |
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分子量 | 1242.4 |
化学式 | C58H79N15O16 |
存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
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Reference | elegrin, P. et al. EMBO. J. 25, 5071 (2006)Pelegrin, P. et al.t J. Biol. Chem. 282, 2386 (2007). |
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