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名称 | Orexin A, human |
编码 | |
别名 | Orexin A, human |
纯度 | 80%,90%,95%,98%,99% |
重量 | 1mg,5mg,10mg,50mg,100mg,1g |
序列(单字母缩写) | Glp-PLPDCCRQKTCSCRLYELLHGAGNHAAGILTL-NH2?(C6&C12 bridge, C7&C14 bridge) |
序列(三字母缩写) | Glp-Pro-Leu-Pro-Asp-Cys-Cys-Arg-Gln-Lys-Thr-Cys-Ser-Cys-Arg-Leu-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2?(trifluoroacetate salt)(Cys6 and 12 bridge, Cys7 and 14 bridge) |
基本描述 | Hypothalamic neuropeptide that regulates feeding behavior and significantly augments food intake in a dose-dependent manner when a bolus is administered intracerebroventricularly. After a 48-hour fast, hypothalamic prpro-orexin mRNA level is up-regulated 2.4. The discovery of orexins and their receptors may provide a novel molecular basis for understanding the role of the lateral hypothalamic areas in the regulation of energy homeostasis. |
溶解度 | |
分子量 | 3561.2 |
化学式 | C152H243N47O44S4 |
存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
注释 | |
Documents | |
Figures | |
Reference | M.W. Schwartz, Nature Med., 4, 385 (1998) T. Sakurai et al., Cell, 92, 573 (1998) |
C端 | |
N端 | |
化学桥 | (Cys6 and 12 bridge, Cys7 and 14 bridge) |