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名称 | Melanocyte-Stimulating Hormone-Release Inh,MSH Release Inhibiting Factor, amide |
编码 | [2002-44-0] |
别名 | Melanocyte-Stimulating Hormone-Release Inh,MSH Release Inhibiting Factor, amide |
纯度 | 80%,90%,95%,98%,99% |
重量 | 1mg,5mg,10mg,50mg,100mg,1g |
序列(单字母缩写) | PLG-NH2 |
序列(三字母缩写) | H-Pro-Leu-Gly-NH2?(trifluoroacetate salt) |
基本描述 | Screening analogs of the cyclic lactam melanocortin agonist MTII led to the identification of the agoutimimetic SHU9119. The cyclopeptide SHU9119 shares pharmacological properties with the agouti peptide in that it is a potent antagonist of the melanocortin-4 receptor and a less potent antagonist of the melanocortin-3 receptor. |
溶解度 | |
分子量 | 284.36 |
化学式 | C13H24N4O3 |
存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
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Reference | S.Bj?rkman and H.Sievertsson, Naunyn-Schmiedeberg’s Arch. Pharmacol., 298, 79 (1977) T.A.Pugsley and W.Lippmann, Drug Res., 27 II, 2290 (1977) S.Chiu and R.K.Mishra, Eur. J. Pharmacol., 53, 119 (1979) R.Walter et al., Proc. Natl. Acad. Sci. USA, 76, 518 (1979) K.Dolbeare et al., Bioorg. Med. Chem., 11, 4103 (2003) R.S.Khan et al., Int. J. Pept., ID 537639 (2010) |
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