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名称 | Insulin B (13 – 23) |
编码 | |
别名 | Insulin B (13 – 23) |
纯度 | 80%,90%,95%,98%,99% |
重量 | 1mg,5mg,10mg,50mg,100mg,1g |
序列(单字母缩写) | EALYLVCGERG |
序列(三字母缩写) | H-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-OH (trifluoroacetate salt) |
基本描述 | This insulin beta-chain peptide binds to a MHC-II allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic beta cells leading to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to autoantibodies and insulitis. |
溶解度 | |
分子量 | 1209.38 |
化学式 | C52H84N14O17S1 |
存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
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