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名称 | GLP-1/Glucagon-Like Peptide-1 (1-36) amide, human |
编码 | [99658-04-5] |
别名 | GLP-1/Glucagon-Like Peptide-1 (1-36) amide, human |
纯度 | 80%,90%,95%,98%,99% |
重量 | 1mg,5mg,10mg,50mg,100mg,1g |
序列(单字母缩写) | HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2 |
序列(三字母缩写) | H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2?(trifluoroacetate salt) |
基本描述 | GLp-1 fragment that is isolated from the lower small intestine and is presently regarded to be the most important incretin hormone. It shows a strong insulinotropic effect that is mediated by receptors expressed in the pancreatic beta-cells. It is proposed to be a novel therapeutic strategy for non-insulin-dependent (type 2) diabetes mellitus and associated neuropathy. |
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分子量 | 4111.5 |
化学式 | C184H273N51O57 |
存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
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Reference | G. Bell et al., Nature, 304, 368 (1983) D.J.Drucker et al., Proc. Natl. Acad. Sci. USA, 84, 3434 (1987) |
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