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名称 | Caspase 8 Substrate 1, chromogenic |
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别名 | Caspase 8 Substrate 1, chromogenic |
纯度 | 80%,90%,95%,98%,99% |
重量 | 1mg,5mg,10mg,50mg,100mg,1g |
序列(单字母缩写) | Ac-IETD-pNA |
序列(三字母缩写) | Ac-Ile-Glu-Thr-Asp-pNA |
基本描述 | pNA (4-nitroaniline)-derived caspase substrates widely used for various caspase activities and colorimetric detection. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm. Caspase-9 substrate. |
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分子量 | 638.6 |
化学式 | C27H38N6O12 |
存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
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Reference | Grutter MG (2000) Curr Opin Struct Biol 10, 649-55 Gastman BR (2001) Head Neck 23, 409-25 Grutter MG (2000) Curr Opin Struct Biol 10, 649-55 Stennicke HR and Salvesen GS (1999)Cell Death Differ 6, 1054-9 Stennicke HR and Salvesen GS (1998) Biochim Biophys Acta 1387, 17-31 Thornberry NA and Lazebnik Y (1998) Science 281, 1312-6 Talanian RV, et al. (1997) . J Biol Chem 272, 9677-82. Fassy F, et al. (1998) Eur J Biochem 253, 76-83 Datta R, et al. (1996) Blood 88, 1936-43 Koeplinger KA, et al. (2000) Protein Expr Purif 18, 378-87 |
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