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名称 | Apopain Substrate |
编码 | [169332-61-0] |
别名 | Apopain Substrate |
纯度 | 80%,90%,95%,98%,99% |
重量 | 1mg,5mg,10mg,50mg,100mg,1g |
序列(单字母缩写) | Ac-DEVD-AMC |
序列(三字母缩写) | Ac-Asp-Glu-Val-Asp-AMC |
基本描述 | Potent inhibitor for the poly(ADP-ribose) polymerase (PARP) cleavage by caspase-3 (IC50=0.2 nM). PARP cleavage occurs at the onset of apoptosis. This peptide aldehyde is useful in attenuating apoptotic events in vitro (IC50 = 10 nM). |
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分子量 | 675.7 |
化学式 | C30H37N5O13 |
存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
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Reference | D.W. Nicholson, Nature, 376 (1995) J. Xiang et al., Proc. Natl. Acad. Sci. USA, 93, 14559 (1996) |
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