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| 名称 | [Lys(Ac)382]-p53 (372-389), biotin labeled |
| 编码 | |
| 别名 | [Lys(Ac)382]-p53 (372-389), biotin labeled |
| 纯度 | 80%，90%，95%，98%，99% |
| 重量 | 1mg,5mg,10mg,50mg,100mg,1g |
| 序列（单字母缩写） | Biotin-LC-KKGQSTSRHK-K(Ac)-LMFKTEG-NH2 |
| 序列（三字母缩写） | Biotin-LC-Lys-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys(Ac)-Leu-Met-Phe-Lys-Thr-Glu-Gly-NH2?(trifluoroacetate salt) |
| 基本描述 | This peptide is a p53 tumor suppressor protein acetylated at lysine 382 upon Ras expression, an event that is essential for its biological function. Acetylation at lysine 382 specifically determines the PAb421 epitope. p53 acts as both a tumor-suppressor and transcription factor that, upon activation by DNA damage and other cellular stress signals, leads to the transcription of genes triggering cell-cycle arrest, apoptosis, and DNA repair |
| 溶解度 | |
| 分子量 | 2472 |
| 化学式 | |
| 存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
| 注释 | |
| Documents | ![[Lys(Ac)382]-p53 (372-389), biotin labeled 编码](http://www.fluoroprobe.com/wp-content/uploads/2022/10/20221013_63489210c5bd8.png) |
| Figures | ![[Lys(Ac)382]-p53 (372-389), biotin labeled 编码](http://www.fluoroprobe.com/wp-content/uploads/2022/10/20221013_6348921126085.jpg) |
| Reference | Kubbutat, M. et al. Lett. Nature 387, 299 (1997) Li, M. et al. J. Biol. Chem. 277, 50607 (2002) |
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