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| 名称 | [Lys(Ac)373]-p53 (368-393), p53 K373(Ac), biotin-labeled, human |
| 编码 | |
| 别名 | [Lys(Ac)373]-p53 (368-393), p53 K373(Ac), biotin-labeled, human |
| 纯度 | 80%，90%，95%，98%，99% |
| 重量 | 1mg,5mg,10mg,50mg,100mg,1g |
| 序列（单字母缩写） | Biotin-KGWHLKSK-K(Ac)-GQSTSRHKKLMFKTEGPDSD-NH2 |
| 序列（三字母缩写） | Biotin-Lys-Gly-Trp-His-Leu-Lys-Ser-Lys-Lys(Ac)-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2(trifluoroacetate salt) |
| 基本描述 | This is an amidated peptide derived from residues 361-393 of human p53 tumor suppressor protein with acetylation at Lys382. This peptide is biotin-labeled at its N-terminus with a 6-carbon LC linker. Activated p53 functions to induce cell cycle arrest and apoptosis in response to signals such as DNA damage. Acetylation of p53 reduces ubiquitination by MDM2 and increases p53 half-life in vivo |
| 溶解度 | |
| 分子量 | 3610.2 |
| 化学式 | |
| 存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
| 注释 | |
| Documents | ![[Lys(Ac)373]-p53 (368-393), p53 K373(Ac), biotin-labeled, human 编码](http://www.fluoroprobe.com/wp-content/uploads/2022/10/20221013_6348922f336ea.png) |
| Figures | ![[Lys(Ac)373]-p53 (368-393), p53 K373(Ac), biotin-labeled, human 编码](http://www.fluoroprobe.com/wp-content/uploads/2022/10/20221013_6348922f85a43.jpg) |
| Reference | Kubbutat, M. et al. Lett Nature 387, 299 (1997) Li, M. et al. J Biol Chem 277, 50607 (2002) |
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