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名称 | [DArg1,DPhe5,DTrp7,9,Leu11] Substance P |
编码 | [96736-12-8] |
别名 | [DArg1,DPhe5,DTrp7,9,Leu11] Substance P |
纯度 | 80%,90%,95%,98%,99% |
重量 | 1mg,5mg,10mg,50mg,100mg,1g |
序列(单字母缩写) | rPKPfQwFwLL-NH2 |
序列(三字母缩写) | H-DArg-Pro-Lys-Pro-DPhe-Gln-DTrp-Phe-DTrp-Leu-Leu-NH2?(trifluoroacetate salt) |
基本描述 | This neuropeptide was found in the gut as well as in the brain. It is responsible for a number of excitatory effects on both central and peripheral neurons. It contracts smooth muscle, constricts bronchioles and increases capillary permeability. When released from afferent nerves, it causes a neurogenic inflammatory response, including mast cell degranulation. |
溶解度 | |
分子量 | 1516.86 |
化学式 | C79H109N19O12 |
存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
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Reference | B.Holst et al., Mol. Endocrinol., 17, 2201 (2003) D.A.Jones et al., Peptides, 16, 777 (1995) J.G.Reeve and N.M.Bleehen, Biochem. Biophys. Res. Commun., 199, 1313 (1994) H.Houben and C.Denef, Peptides, 14, 109 (1993) P.J.Woll and E.Rozengurt, Proc. Natl. Acad. Sci. USA, 85, 1859 (1988) K.Tsou et al., Eur. J. Pharmacol., 110, 155 (1985) |
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