上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Metyrapone (Synonyms: 美替拉酮; Su-4885) 纯度: 99.84%
Metyrapone抑制P450介导的ω/ω-1羟化酶活性和CYP11B1。
Metyrapone Chemical Structure
CAS No. : 54-36-4
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
Free Sample (0.1-0.5 mg) | Apply now | ||
10 mM * 1 mL in DMSO | ¥550 | In-stock | |
100 mg | ¥600 | In-stock | |
500 mg | ¥1800 | In-stock | |
1 g | 询价 | ||
5 g | 询价 |
* Please select Quantity before adding items.
Metyrapone 相关产品
•相关化合物库:
- Drug Repurposing Compound Library Plus
- FDA-Approved Drug Library Plus
- FDA-Approved Drug Library Mini
- Bioactive Compound Library Plus
- Metabolism/Protease Compound Library
- FDA-Approved Drug Library
- Anti-Cancer Compound Library
- Autophagy Compound Library
- Anti-Aging Compound Library
- Drug Repurposing Compound Library
- Antioxidants Compound Library
- Oxygen Sensing Compound Library
- Anti-COVID-19 Compound Library
- Orally Active Compound Library
- FDA Approved & Pharmacopeial Drug Library
- Drug-Induced Liver Injury (DILI) Compound Library
- Rare Diseases Drug Library
生物活性 |
Metyrapone is an inhibitor of cytochrome P450-mediated ω/ω-1 hydroxylase activity and CYP11B1. Target: CYP11B1 Metyrapone is a drug used in the diagnosis of adrenal insufficiency and occasionally in the treatment of Cushing’s syndrome (hypercortisolism). Metyrapone blocks cortisol synthesis by reversibly inhibiting steroid 11β-hydroxylase. This stimulates ACTH secretion, which in turn increases plasma 11-Deoxycortisol levels. |
||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Clinical Trial |
|
||||||||||||||||
分子量 |
226.27 |
||||||||||||||||
Formula |
C14H14N2O |
||||||||||||||||
CAS 号 |
54-36-4 |
||||||||||||||||
中文名称 |
美替拉酮;甲吡酮;米替拉潘 |
||||||||||||||||
运输条件 |
Room temperature in continental US; may vary elsewhere. |
||||||||||||||||
储存方式 |
|
||||||||||||||||
溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (441.95 mM; Need ultrasonic) H2O : ≥ 38 mg/mL (167.94 mM) * “≥” means soluble, but saturation unknown. 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
|
所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务