细胞松弛素B
基本信息
产品名称 | 细胞松弛素B |
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英文名称 | Cytochalasin B |
别名 | 松胞菌素B |
英文别名 | Phomin;(7S),(20R)-Dihydroxy-16(R)-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13(E),21(E)-triene-1,23-dione |
规格或纯度 | 98% |
运输条件 | 超低温冰袋运输 |
生化机理 | One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. .Cell permeable actin polymerization inhibitor. Reversible K V 1.5 blocker (IC 50 = 4 μM). Inhibits I(Kur). Cytochalasin A analog. Inhibits transport of monosaccharides across the cell membrane. Shows antitumor effects in vivo. |
一般描述
Cytochalasin B is used in actin polymerization studies and cytological research. Cytochalasin B is a metabolite of the fungus Drechslera dematoidea which binds to the barbed end of actin filaments resulting in inhibition of both the association and dissociation of subunits. As opposed to other Cytochalasins, cytochalasin A and Cytochalasin B bind to the glucose transporter and inhibit monosaccharide transport across the plasma membrane. Cytochalasin B inhibits phagocytosis by both mononuclear phagocytes and polymorphonuclear leukocytes.A cell-permeable fungal toxin used in actin polymerization studies and cytological
Cytochalasin B is used in actin polymerization studies and cytological research. Cytochalasin B is a metabolite of the fungus Drechslera dematoidea which binds to the barbed end of actin filaments resulting in inhibition of both the association and dissociation of subunits. As opposed to other Cytochalasins, cytochalasin A and Cytochalasin B bind to the glucose transporter and inhibit monosaccharide transport across the plasma membrane. Cytochalasin B inhibits phagocytosis by both mononuclear phagocytes and polymorphonuclear leukocytes
A cell-permeable fungal toxin used in actin polymerization studies and cytological
相关属性
CAS编号 | 14930-96-2 |
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敏感性 | 对热敏感;对光敏感;对湿度敏感 |
熔点 | 218-223°C |
溶解性 | Soluble in methanol (20 mg/ml), and 1:20 DMF:PBS(7.2) (~0.05 mg/ml). |
储存温度 | 避光,-20°C储存,干燥 |
RTECS | RO0205000 |
MDL号 | MFCD00077704 |
密度 | 1.2 |
分子量 | 479.61 |
分子式 | C29H37NO5 |
EC号 | 239-000-2 |
品牌 | Jinpan |
备注 | 如果有可能,您尽量在同一天配置溶液,并在当天使用完它。但是,如果您需要预先配制储备溶液,我们建议您将溶液等份保存在-20°C的密封小瓶中。通常,它们最多可以使用一个月。在使用前和打开样品瓶之前,我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度,用法和处理的建议吗?请访问我们的常见问题(FAQ)页面以获取更多详细信息。 |
PubChem CID | 5311281 |