Cas(58-60-6), 氨基核苷嘌呤霉素, ,Puromycin aminonucleoside,

发表于由

氨基核苷嘌呤霉素

足细胞毒素，诱导ROS和氧化剂依赖性DNA损伤
98%

有货

Cas(58-60-6), 氨基核苷嘌呤霉素,  ,Puromycin aminonucleoside,

CAS编号 58-60-6 | 品牌：Jinpan
Puromycin aminonucleoside

MSDS

质检证书(CoA)

相似产品

  • 分子式 C12H18N6O3
  • 分子量294.31
  • Beilstein号 93902
  • EC号 200-388-3
  • MDL号 MFCD00063462
  • PubChem编号 6020

货号 (SKU) 包装规格 是否现货 价格 数量
P102404-5mg 5mg 现货 Cas(58-60-6), 氨基核苷嘌呤霉素,  ,Puromycin aminonucleoside,  
P102404-25mg 25mg 现货 Cas(58-60-6), 氨基核苷嘌呤霉素,  ,Puromycin aminonucleoside,  
P102404-100mg 100mg 现货 Cas(58-60-6), 氨基核苷嘌呤霉素,  ,Puromycin aminonucleoside,  

基本信息

产品名称 氨基核苷嘌呤霉素
英文名称 Puromycin aminonucleoside
别名 3′-Amino-3′-deoxy-N6,N6-dimethyladenosine;9-(3-Amino-3-deoxy-beta-D-ribofuranosyl)-6-(dimethylamino)-9H-purine; Aminonucleoside; Aminonucleoside puromycin;PANS
英文别名 3′-Amino-3′-deoxy-N6,N6-dimethyladenosine;9-(3-Amino-3-deoxy-beta-D-ribofuranosyl)-6-(dimethylamino)-9H-purine; Aminonucleoside; Aminonucleoside puromycin;PANS
应用 The aminonucleoside portion of the antibiotic puromycin.
规格或纯度 98%
运输条件 超低温冰袋运输
生化机理 Puromycin aminonucleoside is used to study human glomerular disease by inducing damage of murine glomerular podocytes1 and is used to study glomerular function and morphology.Podocyte toxin, induces ROS and oxidant-dependent DNA damage in podocytes. Puromycin analogue that does not inhibit protein synthesis or induce DNA fragmentation. Antibiotic, antineoplastic and antimetabolite agent. Active in vivo and in vitro .

一般描述

Puromycin Aminonucleoside (3′-Amino-3′-deoxy-N6,N6-dimethyladenosine) is the aminonucleoside portion of the antibiotic puromycin. It is a puromycin analog which does not inhibit protein synthesis or induce apoptosis. Used in the study of focal and segmental glomerulosclerosis and in the induction of nephrosis in rats. The excretion of sodium and NOx metabolites in rats with puromycin aminonucleoside-induced nephrotic syndrome has been studied. Used to probe endothelial glycosaminoglycan synthesis in cultured glomerular endothelial cells and their relation to cell permeabilityThe aminonucleoside portion of the antibiotic puromycin.

Puromycin Aminonucleoside (3′-Amino-3′-deoxy-N6,N6-dimethyladenosine) is the aminonucleoside portion of the antibiotic puromycin. It is a puromycin analog which does not inhibit protein synthesis or induce apoptosis. Used in the study of focal and segmental glomerulosclerosis and in the induction of nephrosis in rats. The excretion of sodium and NOx metabolites in rats with puromycin aminonucleoside-induced nephrotic syndrome has been studied. Used to probe endothelial glycosaminoglycan synthesis in cultured glomerular endothelial cells and their relation to cell permeability
The aminonucleoside portion of the antibiotic puromycin.

相关属性

CAS编号 58-60-6
敏感性 对光敏感
溶解性 Soluble in water (10 mg/ml)
储存温度 避光,-20°C储存
MDL号 MFCD00063462
密度 1.7
分子量 294.31
分子式 C12H18N6O3
EC号 200-388-3
品牌 Jinpan
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PubChem CID 6020