青霉酸
Mutagen. Antibiotic mycotoxin.
≥98% (HPLC)
有货
基本信息
产品名称 | 青霉酸 |
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英文名称 | Penicillic acid |
别名 | PA |
英文别名 | 3-Methoxy-5-methyl-4-oxo-2,5-hexadienoic acid;PA |
应用 | Penicillic acid is used to study FasL-induced apoptosis and cell viability in Burkitt′s lymphoma Raji cells,and is used to study bacterial bioluminescence bioassays and genotoxicity of hepatocytes. |
规格或纯度 | ≥98% (HPLC) |
运输条件 | 冰袋运输 |
生化机理 | Penicillic acid is a mycotoxin isolated from various strains of Penicillium and Aspergillus fungi that demonstrates mutagenic and cytotoxic effects. This compound is demonstrated to induce single-strand DNA breaks and to inhibit DNA synthesis in CHO cells. Penicillic acid is also reported to irreversibly inactivate GMD (GDP-mannose dehydrogenase), interrupting the committed step in alginate biosynthesis. Penicillic acid is an inhibitor of ADH/AKR1A1 and LDH.Mutagen. Antibiotic mycotoxin. Induces DNA single-strand breaks. Irreversible GDP-mannose dehydrogenase inhibitor. Inhibits RNA and protein synthesis (ED 50 values are 180 and 600 μM respectively). Glutathione S-transferase inhibitor. |
一般描述
Penicillic acid: a Mycotoxin that induces DNA single-strand breaksPenicillic acid is used to study FasL-induced apoptosis and cell viability in Burkitt′s lymphoma Raji cells,and is used to study bacterial bioluminescence bioassays and genotoxicity of hepatocytes.
Penicillic acid: a Mycotoxin that induces DNA single-strand breaks
Penicillic acid is used to study FasL-induced apoptosis and cell viability in Burkitt′s lymphoma Raji cells,and is used to study bacterial bioluminescence bioassays and genotoxicity of hepatocytes.
相关属性
CAS编号 | 90-65-3 |
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熔点 | 83°C-87°C |
溶解性 | Soluble in water (50 mg/ml), DMSO (>10 mg/ml), chloroform (10 mg/ml), ethyl acetate (>10 mg/ml), and acetonitrile (>10 mg/ml) |
储存温度 | 2-8°C储存 |
MDL号 | MFCD00004365 |
分子量 | 170.16 |
分子式 | C8H10O4 |
EC号 | 202-008-1 |
品牌 | Jinpan |
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PubChem CID | 7025 |