盐酸土霉素
BP2007,药用级
有货
基本信息
| 产品名称 | 盐酸土霉素 |
|---|---|
| 英文名称 | Oxytetracycline hydrochloride |
| 别名 | 盐酸氧四环素 |
| 英文别名 | 5-Hydroxytetracycline hydrochloride |
| 应用 | 靠阻止氨基酰-tRNA结合到30S亚单位上抑制蛋白合成。 抗菌谱: 革兰氏阴性和阳性细菌。 耐药性模式: 活性丧失， 核糖体保护, 四环素失活。 |
| 规格或纯度 | BP2007,药用级 |
| 运输条件 | 冰袋运输 |
| 生化机理 | Oxytetracycline inhibits translation which results in cell death. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic so it can easily pass throμgh a cell membrane and passively diffuses throμgh channels in the bacterial membrane. |
一般描述
溶解度:>100 g/L水，20 g/L 甲醇。
Oxytetracycline is a tetracycline analog isolated from the actinomycete streptomyces rimosus. Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistanc?e gene (otrA). Oxytetracycline hydrochloride is used to study phagosome-lysosome (P-L) fusion in P388D1 cells and antibiotic susceptibilities of Mycopasma bovis isolates.
相关属性
| CAS编号 | 2058-46-0 |
|---|---|
| 比旋光度 | -172° (C=1,1mol/L HCl) |
| 熔点 | 180°C |
| 储存温度 | 2-8°C储存 |
| RTECS | QI8225000 |
| MDL号 | MFCD00135815 |
| 密度 | 1.71 |
| 分子量 | 496.89 |
| 分子式 | C22H24N2O9·HCl |
| EC号 | 218-161-2 |
| 品牌 | Jinpan |
| PubChem CID | 54675779 |