Cinoxacin

Cinoxacin

10mM in DMSO

有货

Cinoxacin

CAS编号 28657-80-9 | 品牌:Jinpan
Cinoxacin

MSDS

质检证书(CoA)

相似产品

  • 分子式 C12H10N2O5
  • 分子量262.22
  • EC号 249-133-8
  • PubChem编号 2762

货号 (SKU) 包装规格 是否现货 价格 数量
C423002-1ml 1ml 期货 Cinoxacin  

基本信息

产品名称 Cinoxacin
英文名称 Cinoxacin
别名 西诺沙星
英文别名 1-Ethyl-1,4-dihydro-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid
规格或纯度 10mM in DMSO
运输条件 超低温冰袋运输
生化机理 Cinoxacin interferes with DNA replication by inhibiting DNA gyrase and topoisomerase IV (topo IV) through tight DNA binding. Cinoxacin allows for proper replicated DNA separation. Therefore, the inhibition of Cinoxacin inhibits DNA replication and cell division.

一般描述

Cinoxacin is an antibacterial quinolone analog of oxolinic acid. The compound has been documented to block DNA synthesis through inhibition of Topo II (DNA gyrase) as well as topoisomerase IV. Cinoxacin has been observed to block both topoisomerse IV in both prokaryotic and eukaryotic cell lines. Due to the inhibiting activity of Cinoxacin the compound has displayed toxicity against eukaryotic cells. In vitro studies have shown the renal damage caused by Cinoxacin to be attributed to deposition of Cinoxacin crystals in the urinary tract.

product description:

Cinoxacin is an antibacterial quinolone analog of oxolinic acid. The compound has been documented to block DNA synthesis throμgh inhibition of Topo II (DNA gyrase) as well as topoisomerase IV. Cinoxacin has been observed to block both topoisomerse IV in both prokaryotic and eukaryotic cell lines. Due to the inhibiting activity of Cinoxacin the compound has displayed toxicity against eukaryotic cells. In vitro studies have shown the renal damage caused by Cinoxacin to be attributed to deposition of Cinoxacin crystals in the urinary tract.Cinoxacin is a synthetic antimicrobial commonly used in urinary tract infections that are caused by Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species, and Enterobacter species.. It is a quinolone gyrase inhibitor. It is used to study the rat renal organic anion transporter 1 (OAT1). It is used to study fluoroquinolone-resistant Streptococcus pyogenes.

相关属性

CAS编号 28657-80-9
储存温度 -80℃储存
分子量 262.22
分子式 C12H10N2O5
EC号 249-133-8
品牌 Jinpan
PubChem CID 2762