非达霉素
10mM in DMSO
有货
基本信息
| 产品名称 | 非达霉素 |
|---|---|
| 英文名称 | Fidaxomicin |
| 别名 | 非达霉素 |
| 英文别名 | OPT-80, PAR-101;Oxacyclooctadeca-3,5,9,13,15-pentaen-2-one, 3-[[[6-deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hy |
| 规格或纯度 | 10mM in DMSO |
| 运输条件 | 超低温冰袋运输 |
| 生化机理 | Fidaxomicin is a recently approved antibiotic with a confusing history dating back to its original isolation in 1975. Fidaxomicin is the major analogue of a family of macrocyclic lactones isolated independently by three different groups from cultures belonging to three different genera (Actinoplanes, Dactylosporangium and Micromonospora) known as lipiarmycin A3, tiacumicin B and clostomicin B1, respectively. Fidaxomicin is a narrow spectrum antibiotic with excellent activity against Gram positive bacteria, notably Clostridium difficile. Fidaxomicin acts in the gastrointestinal tract without undue disruption to gut microbial flora. |
一般描述
Fidaxomicin 是一种窄谱的大环类抗生素，抑制RNA聚合酶σ亚基。
Fidaxomicin is a narrow spectrum macrocyclic antibiotic that inhibits RNA polymerase sigma subunit.
A macrocyclic antibiotic.
相关属性
| CAS编号 | 873857-62-6 |
|---|---|
| 敏感性 | 对热敏感 |
| 比旋光度 | -6.9° (C=2,MeOH) |
| 熔点 | 161 °C |
| 储存温度 | -80℃储存 |
| 分子量 | 1058.04 |
| 分子式 | C52H74Cl2O18 |
| 品牌 | Jinpan |
| PubChem CID | 10034073 |