磷霉素二钠盐
基本信息
| 产品名称 | 磷霉素二钠盐 |
|---|---|
| 英文名称 | Fosfomycin Disodium Salt |
| 别名 | (1R,2S)-1,2-环氧丙基磷酸二钠盐 |
| 英文别名 | (1R,2S)-1,2-Epoxypropylphosphonic Acid Disodium Salt; Disodium (1R,2S)-1,2-Epoxypropylphosphonate |
| 规格或纯度 | 10mM in Water |
| 运输条件 | 超低温冰袋运输 |
| 生化机理 | Antibiotic that concentrates in kidney and bladder; reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. Fosfomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme involved in bacterial cell wall biosynthesis. As a result, the production of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall, is inhibited.Broad spectrum antimicrobial agent. Inhibits cell wall synthesis in Gram-negative and Gram-positive bacteria. Pharmacologically active following intravenous administration. Crosses the blood-brain barrier. |
一般描述
Phosphomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae. It is used to treat uncomplicated urinary tract infections and to reduce nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. It is used for susceptibility studies of Klebsiella pneumoniae and to study in vitro susceptibility testing procedures for fosfomycin tromethamine
Phosphomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae. It is used to treat uncomplicated urinary tract infections and to reduce nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. It is used for susceptibility studies of Klebsiella pneumoniae and to study in vitro susceptibility testing procedures for fosfomycin tromethamine
相关属性
| CAS编号 | 26016-99-9 |
|---|---|
| 敏感性 | 对热敏感 |
| 比旋光度 | -5° (C=5,H2O) |
| 储存温度 | -80℃储存 |
| 分子量 | 182.02 |
| 分子式 | C3H5Na2O4P |
| EC号 | 247-409-2 |
| 品牌 | Jinpan |
| 关联CAS | 23155-02-4 |
| PubChem CID | 73491 |