弗吉尼亚霉素复合物

弗吉尼亚霉素复合物是75％维吉尼亚霉素M1（维吉尼霉素 A，sc-202269）和25％维吉尼亚霉素S1的固体粉末混合物，两种链霉菌素抗生素具有协同杀菌作用。弗吉尼亚霉素M1抑制50S核糖体亚基的功能，而不会阻止其组装，从而产生抑菌作用。加入维吉尼亚霉素S1成分后，弗吉尼亚霉素复合物具有杀菌作用，表明这两种化合物与核糖体缔合后会发生相互作用。如果将弗吉尼亚霉素复合物用于牲畜，可能会改善生长。弗吉尼亚霉素复合物可以控制细菌与燃料乙醇发酵罐中的酵母竞争。

Virginiamycin Complex is a solid powder mixture of 75% virginiamycin M1 (Ostreogrycin A, sc-202269) and 25% virginiamycin S1, two streptogramin antibiotics which present a synergistic bacteriocidal action. Virginiamycin M1 inhibits the function of the 50S ribosomal subunit without blocking its assembly, producing a bacteriostatic effect. With the addition of the virginiamycin S1 component, the Virginiamycin Complex presents bacteriocidal effects, indicating an interaction between the two compounds upon their association with the ribosome. Virginiamycin Complex, when given to livestock, may improve growth. Virginiamycin Complex can control bacteria competing with yeast in fuel ethanol fermenters.