16,16-二甲基前列腺素A1
PGA1的抗代谢类似物
A solution in methyl acetate
有货
基本信息
| 产品名称 | 16,16-二甲基前列腺素A1 |
|---|---|
| 英文名称 | 16,16-dimethyl Prostaglandin A1 |
| 英文别名 | 16,16-dimethyl PGA1 |
| 规格或纯度 | A solution in methyl acetate |
| 运输条件 | 超低温冰袋运输 |
一般描述
16,16-二甲基前列腺素A1是PGA1的抗代谢类似物，在体外不会抑制细胞DNA合成的浓度抑制HSV和HIV-1感染系统中的病毒复制。Vero细胞和人包皮成纤维细胞中HSV-1菌株的ID | 50 |值分别为3.8-5.6 µg / ml和4.6-7.3 µg / ml。急性感染HIV-1的T细胞的ID | 50 |为2.5 µg / ml。
16,16-dimethyl Prostaglandin A1 is a metabolism resistant analog of PGA1 that inhibits the viral replication in both HSV and HIV-1 infection systems|in vitro|at concentrations that do not adversely alter cellular DNA synthesis. The ID|50|values for HSV-1 strains in vero cells and human foreskin fibroblasts are 3.8-5.6 μg/ml and 4.6-7.3 μg/ml, respectively. The ID|50|for T cells acutely infected with HIV-1 is 2.5 μg/ml.
相关属性
| CAS编号 | 41692-24-4 |
|---|---|
| 沸点 | 57-58° C (lit.)(methyl acetate) |
| 储存温度 | -20°C储存 |
| 分子量 | 364.5 |
| 分子式 | C₂₂H₃₆O₄ |
| 品牌 | Jinpan |
| Smiles | CCCCC(C)(C)[C@@H](/C=C/[C@H]1C=CC(=O)[C@@H]1CCCCCCC(=O)O)O |
| PubChem CID | 5271806 |