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STL127705 纯度: ≥98.0%
STL127705 (Compound L) 是一种 Ku 70/80 异二聚体蛋白 (Ku 70/80 heterodimer protein) 抑制剂,抑制 Ku70/80-DNA 相互作用,IC50 值为 3.5 μM。STL127705 可抑制 Ku 依赖性 DNA-PKCS 激酶的活化,IC50 值为 2.5 μM。
STL127705 Chemical Structure
CAS No. : 1326852-06-5
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥3500 | In-stock | |
10 mg | ¥5500 | In-stock | |
25 mg | ¥9900 | In-stock | |
50 mg | ¥16500 | In-stock | |
100 mg | ¥22500 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
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STL127705 相关产品
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生物活性 |
STL127705 (Compound L) is a Ku 70/80 heterodimer protein inhibitor, inhibits Ku70/80-DNA interaction, with an IC50 of 3.5 μM. STL127705 also inhibits Ku-dependent activation of DNA-PKCS kinase (IC50, 2.5 μM)[1]. |
IC50 & Target |
IC50: 3.5 μM (Ku 70/80), 2.5 μM (DNA-PKCS)[1] |
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分子量 |
437.42 |
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Formula |
C22H20FN5O4 |
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CAS 号 |
1326852-06-5 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
H2O : < 0.1 mg/mL (insoluble) DMSO : < 1 mg/mL (insoluble or slightly soluble) *STL127705 is usually formulated as a suspension. |
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参考文献 |
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