3,3',5-三碘-L-甲腺原氨酸
10mM in DMSO
有货
基本信息
| 产品名称 | 3,3',5-三碘-L-甲腺原氨酸 |
|---|---|
| 英文名称 | 3,3′,5-Triiodo-L-thyronine |
| 别名 | T3 碘噻罗宁；O-(4-羟基-3-碘苯基)-3,5-二碘代-L-酪氨酸 |
| 英文别名 | Liothyronine;O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine;HY-A0070A; L-3,3′,5-Triiodothyronine;Tresitope |
| 规格或纯度 | 10mM in DMSO |
| 运输条件 | 超低温冰袋运输 |
| 生化机理 | 3,3′,5-Triiodo-L-thyronine also referred to as O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine or T3 is the biologically active thyroid hormone. In hypothyroidism pateints, triiodothyronine enhances mood and neuropsychological function. The product also positively regulates the hepatic FGF21 expression and stimulates the metabolic breakdown of glucose, fats, and proteins by enhancing the levels of numerous metabolic enzymes such as hexokinase, liver glucose 6-phosphatase as well as mitochondrial enzymes for oxidative phosphorylation. Additionally, the product facilitates the normal body growth in children and is pivotal for central nervous system maturation in foetus |
一般描述
3,3′,5-Triiodo-L-thyronine是由前甲状腺素(T4)脱碘生成的甲状腺素，是甲状腺素受体TRα/TRβ的激动剂
3,3′,5-Triiodo-L-thyronine is the most potent form of thyroid hormone, a potent agonist of both thyroid hormone receptors TRα and Trβ with Kis of 2.3 nM for both.
3,3′,5-Triiodo-L-thyronine can be used for Insulin-like growth factor I assays performed by using a double antibody radioimmunoassay. The product can also be used for in vitro transfection of 293T cells.
安全信息
| Merck Index | 5510 |
|---|
相关属性
| CAS编号 | 6893-02-3 |
|---|---|
| 敏感性 | 对光线敏感 |
| 比旋光度 | 23° (C=5,1mol/L HCl:EtOH=1:2) |
| 熔点 | 234-238°C |
| 储存温度 | -80℃储存 |
| Reaxys-RN | 2710227 |
| RTECS | AY6750000 |
| 分子量 | 650.98 |
| 分子式 | C15H12I3NO4 |
| 品牌 | Jinpan |