盐霉素，现成溶液

Description

Chemical structure: polyetherSalinomycin, Ready Made Solution has been used as an inhibitor of endocytosis in primary pancreatic tumor cells. It has also been used in sequential treatment of cancer cells to study resistance.

Preparation instructions

Form

The product is supplied as a 2 mg/mL (2.66 mM) solution in DMSO, 0.2 μm-filtered.

Principle

放线菌素 D 溶液 来源于链霉菌 属

制备说明

The 2 mg/mL solution may be further diluted in an appropriate buffer prior to use.

来自卡那霉素链霉菌的卡那霉素溶液

General Description

Kanamycin sulfate is a broad spectrum aminoglycoside-antibiotic derived from Streptomyces kanamyceticus . It is used as an additive in culture media for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium. Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene. It is recommended for use in cell culture applications at 2 mL/L.

Application

Kanamycin solution from Streptomyces kanamyceticus has been used: to induce deafness in neonatal rats as an endothelial growth medium component for culturing human umbilical vein endothelial cells (HUVECs) as medium component for Mycobacteria Cultures and Top10 E coli cells

来自卡那霉素链霉菌的卡那霉素溶液

General Description

Chemical structure: aminoglycoside

Application

Kanamycin sulfate is a broad spectrum aminoglycoside-antibiotic derived from Streptomyces kanamyceticus . It is used as an additive in culture media for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium. Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene. It is recommended for use in cell culture applications at 10 ml/L.

多粘菌素B 溶液

制备说明

This product is concentrated at 20 mg/mL in water, and should be stored at Store at 2-8°C.

General Description

Polymyxin B sulfate is a strongly cationic cyclic polypeptide antibiotic that is derived from fermentation of Bacilus polymyxa. It is a mixture of B1 and B2 sulfate. The product has been used clinically to treat infections of the urinary tract, meninges and blood stream caused by susceptible strains of Pseudomonas aeruginosa .

Application

Polymyxin B is used to study multidrug-resistant pathogens, as an immobilized agent for removal of endotoxins, and to induce pore formation in the membranes of cortex cells from excised sorghum roots.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.Handle and store under inert gas.

庆大霉素 溶液

General Description

Gentamicin, also known as gentiomycin C, is an aminoglycoside, which is naturally produced by Gram-negative bacteria. This antibiotic functions by preventing protein synthesis. Gentamicin sulfate prevents the growth of both Gram positive and Gram negative bacteria, in vivo and in vitro . In tissue culture, gentamicin sulfate is used to inhibit the growth of various strains of mycoplasma.

Application

Gentamicin solution has been used as an antibiotic component in eukaryotic cell culture and bacterial culture. Gentamicin sulfate is a broad-spectrum antibiotic used as a selection agent (gentamicin-resistance gene) in molecular biology and cell culture applications. This product is formulated to contain 50 mg/mL Gentamicin in deionized water and is recommended for use in eukaryotic cell culture at a volume of 1 milliliter per liter. Gentamicin sulfate solution has been used as a component of different types of culture media.

General Description

Gentamicin, also known as gentiomycin C, is an aminoglycoside, which is naturally produced by Gram-negative bacteria. This antibiotic functions by preventing protein synthesis. Gentamicin sulfate prevents the growth of both Gram positive and Gram negative bacteria, in vivo and in vitro . In tissue culture, gentamicin sulfate is used to inhibit the growth of various strains of mycoplasma.

Application

Gentamicin solution has been used as an antibiotic component in eukaryotic cell culture and bacterial culture. Gentamicin sulfate is a broad-spectrum antibiotic used as a selection agent (gentamicin-resistance gene) in molecular biology and cell culture applications. This product is formulated to contain 50 mg/mL Gentamicin in deionized water and is recommended for use in eukaryotic cell culture at a volume of 1 milliliter per liter. Gentamicin sulfate solution has been used as a component of different types of culture media.

庆大霉素 溶液

一般描述

化学结构：氨基糖苷类

应用

硫酸庆大霉素，是一种广谱抗生素，在分子生物学和细胞培养应用中作为选择剂（庆大霉素抗性基因）。该产品以10 mg/mL庆大霉素浓度在去离子水中配制，建议用于真核细胞培养，每升添加1毫升。

General Description

Chemical structure: aminoglycoside

Application

Gentamicin sulfate is a broad-spectrum antibiotic used as a selection agent (gentamicin-resistance gene) in molecular biology and cell culture applications. This product is formulated to contain 10 mg/mL Gentamicin in deionized water and is recommended for use in eukaryotic cell culture at a volume of 1 milliliter per liter.

庆大霉素 溶液

General Description

Chemical structure: aminoglycoside

Application

Gentamicin solution has been used to study its dose-related antipruritic effects on serotonin (5-HT)-induced scratching model. It has also been used in electrophysiological analysis.

General Description

Chemical structure: aminoglycoside

Application

Gentamicin solution has been used to study its dose-related antipruritic effects on serotonin (5-HT)-induced scratching model. It has also been used in electrophysiological analysis.

庆大霉素-谷氨酰胺溶液

Description

Chemical structure: aminoglycosideGentamicn-Glutamine solution is used for selection of transformed cells that contain the aacA.aphD gene, and is recommended for use in cell culture applications at 10 mL/L.

Description

Chemical structure: aminoglycosideGentamicn-Glutamine solution is used for selection of transformed cells that contain the aacA.aphD gene, and is recommended for use in cell culture applications at 10 mL/L.

制霉菌素即用型溶液

一般描述

制霉菌素是多烯大环内酯类抗真菌药，它是由 诺尔斯氏链霉菌 ATCC 11455 生产的聚酮化合物。该抗生素含有一个大内酯环，其天然合成是通过乙酰辅酶 A 起始的，然后缩合三个乙基丙二酰辅酶 A 和 15 个丙二酰辅酶 A 延伸部分。 化学结构：多烯

应用

制霉菌素已用于- 处理人巨噬细胞 U937，研究制霉菌素对银纳米颗粒处理的 U937 细胞系产生 IL-8（白介素8）的影响 确定其对 COS-7 细胞系中 SR-BI（B 类清道夫受体）介导的 OxLDL（氧化的低密度脂蛋白）细胞内积累的影响 作为小鼠巨噬细胞中的脂质巨噬细胞调节剂，研究脂质筏数目增加与 TNF-α（肿瘤坏死因子）应答增强之间的关系 制霉菌素是一种多烯类抗生素。 它的用途包括防止细胞培养物污染，并在表达 TLR2 的 THP1 细胞中诱导白介素（IL）-1、IL-8 和肿瘤坏死因子 α 分泌。 该产品的推荐细胞培养使用浓度为50 mg/L。

其他说明

保存于密封容器内，置于干燥通风处。在惰性气体下储存。对空气和光敏感。置于干燥处保存。

制备说明

在28°C，制霉菌素可溶于甲醇（11.2 mg/mL）、乙醇（1.2 mg/mL）、四氯化碳（1.23 mg/mL）、氯仿（0.48 mg/mL）、苯（0.28 mg/mL）和乙二醇（8.75 mg/mL）。 也可以5 mg/mL溶于DMSO，易溶于DMF和甲酰胺。 不建议对制霉菌素溶液进行高压灭菌或无菌过滤。 制霉菌素混悬液也有效，37°C下可稳定保存3天。 制备在水中的 50 mg/mL 悬浮液，并储存于 -20°C。

General Description

Chemical structure: polyene Nystatin is a polyene macrolide antifungal, which is a polyketide produced by Streptomyces noursei ATCC 11455. This antibiotic contains a macrolactone ring, and its natural synthesis is initiated with acetyl CoA, which is followed by the condensation of three ethylmalonyl-CoA and 15 malonyl-CoA extender moieties.

Application

Nystatin has been used – for the treatment of human macrophage cell line U937, to study the effect of nystatin on the production of IL-8 (interleukin 8) by silver nanoparticle-treated U937 cell line to determine its effect on intracellular accumulation of OxLDL (oxidized low density lipoprotein) mediated by SR-BI (scavenger receptor class B type I) in COS-7 cell line as a lipid raft modulator on mice macrophages to study the relationship between increased number of lipid rafts and the heightened response of TNF-α (tumor necrosis factor) Nystatin is a polyene antibiotic. Its uses include preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor α secretion in TLR2-expressing THP1 cells. This product is recommended for use in cell culture applications at 50 mg/L.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Store under inert gas. Air and light sensitive. Keep in a dry place.

制霉菌素即用型溶液

一般描述

制霉菌素是一种抑制真菌和杀真菌的多烯抗生素。它与麦角甾醇结合，可增加敏感真菌的细胞膜通透性。制霉菌素主要对念珠菌属有临床活性。然而，据报道它对抗曲霉菌、球孢子菌、新型隐球菌、荚膜组织胞浆菌、芽孢杆菌和其他酵母和真菌也有效。制霉菌素也被用于通过酵母中的阴性选择来富集突变体。据报道，制霉菌素对酿酒酵母的最小抑制浓度（MIC）为 3μg/ml，而对于白色念珠菌的临床分离株，最小抑制浓度为 4-16μg/ml。

General Description

Nystatin is a fungistatic and fungicidal polyene antibiotic. It binds to ergosterol which increases cell membrane permeability in sensitive fungi. Nystatin is mainly clinically active against Candida species. However, it is also reported to be effective against Aspergillus, Coccidioides immitis, Cryptococcus neoformans, Histoplasma capsulatum, Blastomyces dermatidis, and other yeasts and fungi. Nystatin has also been used to enrich mutants by negative selection in yeasts. The minimum inhibitory concentration (MIC) of Nystatin to Saccharomyces cerevisiae was reported to be 3μg/ml while for clinical isolates of Candida albicans the MIC was reported to be 4-16μg/ml.

制霉菌素即用型溶液

一般描述

化学结构：多烯

应用

制霉菌素是一种多烯类抗生素。 用途包括预防培养细胞污染，诱导表达TLR2的THP1细胞分泌白介素（IL）-1、IL-8和肿瘤坏死因子α。 该产品的推荐细胞培养使用浓度为50 mg/L。

其他说明

将容器密闭保存在干燥和通风良好的地方。在惰性气体下保存。对空气和光敏感。在干燥处保存。

制备说明

在28 °C，制霉菌素可溶于甲醇（11.2 mg/mL）、乙醇（1.2 mg/mL）、四氯化碳（1.23 mg/mL）、氯仿（0.48 mg/mL）、苯（0.28 mg/mL）和乙二醇（8.75 mg/mL）。 也可以5 mg/mL溶于DMSO，易溶于DMF和甲酰胺。 不建议对制霉菌素溶液进行高压灭菌或无菌过滤。 制霉菌素混悬液也有效，37 °C下可稳定保存3天。 制备50 mg/mL的储备混悬液，-20°C下保存。对N6261进行γ-辐照得该产品。

General Description

Chemical structure: polyene

Application

Nystatin is a polyene antibiotic. Its uses include preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in TLR2-expressing THP1 cells. This product is recommended for use in cell culture applications at 50 mg/L.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Store under inert gas.Air and light sensitive.Keep in a dry place

两性霉素 B 溶液

一般描述

两性霉素B是一种大环内酯，具有亲水性多羟基链和亲脂性多烯烃链。

应用

两性霉素B溶液已被用于： 作为腹腔注射剂用于治疗 烟曲霉 感染小鼠 作为中国美利奴绵羊卵巢培养的理想培养基的组成部分 在收集马黄体时用作运输培养基中的组成成分 作为RPMI培养基中的补充剂，用于培养小鼠-小鼠B细胞杂交瘤55-6细胞系

其他说明

保存于密闭容器内，置于干燥通风处。光敏感。

制备说明

其在水溶液中形成沉淀是正常现象。 对溶液进行混合可重新溶解大部分沉淀物，但是，如果无法完全溶解，两性霉素B仍然适合使用。

General Description

Amphotericin B is a macrocyclic lactone with a hydrophilic polyhydroxyl chain and a lipophilic polyene based hydrocarbon chain.

Application

Amphotericin B solution has been used: as an intraperitoneal injection for the treatment of Aspergillus fumigatus infection in mice as a constituent of aspiration medium for the culture of Chinese Merino ewe ovaries as a constituent of transport medium during the collection of equine corpora lutea as a supplement in RPMI medium for the culture of the mouse-mouse B cell hybridoma 55-6 cell line

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Light sensitive.

G 418 二硫酸盐 溶液

一般描述

化学结构：氨基糖苷类

应用

G418二硫酸盐是一种氨基糖苷类抗生素，其结构与庆大霉素相似，用于选择和维持原核和真核细胞。不同细胞系具有不同的筛选和维持最佳浓度。 细菌和藻类最多需要5 μg/mL而动物细胞则可能需要300-500 μg/mL。

General Description

Chemical structure: aminoglycoside

Application

G418 disulfate is an aminoglycoside antibiotic similar in structure to gentamicin used for selection and maintenance of prokaryotic and eukaryotic cells. Optimal concentrations for selection and maintenance vary by cell lines. Bacteria and algae require 5 μg/mL or less while animal cells may require 300-500 μg/mL.

泰乐菌素 溶液

制备说明

This product was formulated to contain 8 mg/ml tylosin in 0.9% sodium chloride.

General Description

Chemical structure: macrolide Tylosin is a macrolide antibiotic, which comprises of a 16-member lactone ring. This solution is recommended for use at 1 mL/L.

Application

Tylosin solution has been used as an antimicrobial agent in antibiotic susceptibility minimal inhibitory concentration(MIC) of E. coli and S. aureus isolates. It has also been used as a component of Dulbecco′s modified Eagle′s (DMEM) medium for self-inactivating lentivirus production and skin fibroblast cultivation.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

新霉素溶液

描述

化学结构：氨基糖苷类

应用

新霉素溶液可用于：作为骨髓移植用高压灭菌酸化水的补充剂筛选稳定的克隆作为人工海水（ASWO）培养基的组分，以从O. tauri培养物中去除细菌

Description

Chemical structure: aminoglycosideNeomycin solution has been used:as a supplement of autoclaved acidified water for bone marrow transplantationfor the selection of stable clonesas a component of artificial sea water (ASWO) medium to remove bacteria fromO. tauricultures

甲醇中咪鲜胺溶液标准物质

用途
本标准物质可作为工作标准，用于日常分析和检测；也可用于仪器校准、分析方法确认与评价、测量过程质量控制及技术仲裁与认证评价等。

样品制备

本标准物质采用纯度经准确定值的咪鲜胺( CAS : 67747-09-5 )为溶质，以甲醇为溶剂，在室温20±3℃洁净实验室中采用重量-容量法配制而成。

特征量值及扩展不确定度

标准值的扩展不确定度主要由原料纯度、称量、定容以及均匀性、长期稳定性等不确定度合成。

包装、储存及使用

包装:本标准物质采用包装,规格1.2mL携带或运输时应有防碎裂保护。储存及使用:冷藏密闭及避光条件下保存。使用前应于室温(20±3℃)平衡,并充分摇动以保证均匀。安瓿瓶一经打开,应立即使用，不可再次熔封后作为标准物质使用,使用中严格防止沾污。

Application
This standard substance can be used as a working standard for daily analysis and testing; it can also be used for instrument calibration, analytical method confirmation and evaluation, measurement process quality control, and technical arbitration and certification evaluation.

Sample Preparation

This standard substance is prepared using prochloraz (CAS: 67747-09-5) whose purity has been accurately determined as the solute, methanol as the solvent, and the weight-volume method in a clean laboratory at room temperature of 20±3°C.

Characteristic value and expanded uncertainty

The expanded uncertainty of the standard value is mainly synthesized by the uncertainty of raw material purity, weighing, constant volume, uniformity, and long-term stability.

Packaging, storage and use

Packaging: This standard material is packaged, and the specification 1.2mL should be protected from shattering when carried or transported. Storage and use: Keep it under refrigerated airtight and protected from light. Before use, it should be balanced at room temperature (20±3℃) and shake well to ensure uniformity. Once the ampoule is opened, it should be used immediately. It cannot be used as a standard substance after being re-sealed. Strictly prevent contamination during use.

甲醇中咪鲜胺溶液标准物质

用途
本标准物质可作为工作标准，用于日常分析和检测；也可用于仪器校准、分析方法确认与评价、测量过程质量控制及技术仲裁与认证评价等。

样品制备

本标准物质采用纯度经准确定值的咪鲜胺( CAS : 67747-09-5 )为溶质，以甲醇为溶剂，在室温20±3℃洁净实验室中采用重量-容量法配制而成。

特征量值及扩展不确定度

标准值的扩展不确定度主要由原料纯度、称量、定容以及均匀性、长期稳定性等不确定度合成。

包装、储存及使用

包装:本标准物质采用包装,规格1.2mL携带或运输时应有防碎裂保护。储存及使用:冷藏密闭及避光条件下保存。使用前应于室温(20±3℃)平衡,并充分摇动以保证均匀。安瓿瓶一经打开,应立即使用，不可再次熔封后作为标准物质使用,使用中严格防止沾污。

Application
This standard substance can be used as a working standard for daily analysis and testing; it can also be used for instrument calibration, analytical method confirmation and evaluation, measurement process quality control, and technical arbitration and certification evaluation.

Sample Preparation

This standard substance is prepared using prochloraz (CAS: 67747-09-5) whose purity has been accurately determined as the solute, methanol as the solvent, and the weight-volume method in a clean laboratory at room temperature of 20±3°C.

Characteristic value and expanded uncertainty

The expanded uncertainty of the standard value is mainly synthesized by the uncertainty of raw material purity, weighing, constant volume, uniformity, and long-term stability.

Packaging, storage and use

Packaging: This standard material is packaged, and the specification 1.2mL should be protected from shattering when carried or transported. Storage and use: Keep it under refrigerated airtight and protected from light. Before use, it should be balanced at room temperature (20±3℃) and shake well to ensure uniformity. Once the ampoule is opened, it should be used immediately. It cannot be used as a standard substance after being re-sealed. Strictly prevent contamination during use.

甲醇中叶菌唑溶液