克拉霉素，现成溶液
基本信息
| 产品名称 |
克拉霉素，现成溶液 |
| 英文名称 |
Clarithromycin, Ready Made Solution |
| 别名 |
6-O-methyl erythromycin |
| 英文别名 |
6-O-methyl erythromycin |
| 规格或纯度 |
50 mg/mL in DMSO |
| 生化机理 |
Macrolides, such as clarithromycin, prevent protein synthesis in bacteria, by binding to 50S ribosomal subunit. It also binds to other ribosomal proteins, and prevents the translocation of pepti-dyl-tRNA. In patients with refractory asthma, it is capable of regulating the levels of interleukin-8 (IL-8), and neutrophil accumulation and activation in lungs. Thus, it might be used as an additional therapy in asthma to reduce noneosinophilic airway inflammation. |
一般描述
General Description
Clarithromycin is a macrolide antibiotic, which has both antibacterial and anti-inflammatory actions. It is a semi-synthetic 14-membered derivative of erythromycin A, which is resistant to degradation under acidic conditions.
Application
Clarithromycin may be used for- the study of the effects of clarithromycin on rate-dependent changes in QT, T p-e and proarrhythmic events performed on arterially perfused rabbit left ventricular wedge preparations the culture of parasites expressing GFP (green fluorescence protein) targeted to the apicoplast, to be further used for microscopy-based assays the study of the synergism of NAB741 with clarithromycin in microtiter plates.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Combustible liquids
General Description
Clarithromycin is a macrolide antibiotic, which has both antibacterial and anti-inflammatory actions. It is a semi-synthetic 14-membered derivative of erythromycin A, which is resistant to degradation under acidic conditions.
Application
Clarithromycin may be used for- the study of the effects of clarithromycin on rate-dependent changes in QT, T p-e and proarrhythmic events performed on arterially perfused rabbit left ventricular wedge preparations the culture of parasites expressing GFP (green fluorescence protein) targeted to the apicoplast, to be further used for microscopy-based assays the study of the synergism of NAB741 with clarithromycin in microtiter plates.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Combustible liquids
相关属性
| CAS编号 |
81103-11-9 |
| 比旋光度 |
-92°C |
| 熔点 |
225°C |
| 储存温度 |
干燥 |
| RTECS |
KF4997000 |
| 分子量 |
747.95 |
| 分子式 |
C38H69NO13 |
| 品牌 |
Jinpan |
| PubChem CID |
84029 |
