标签归档：antennapedia

Antennapedia Peptide(Synonyms: 黑腹果蝇触足肽)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Antennapedia Peptide (Synonyms: 黑腹果蝇触足肽)

Antennapedia Peptide 是由 16 个氨基酸残基组成的多肽，来源于果蝇转录因子 Antennapedia 的 60 个氨基酸序列的同源域，它同时是一种穿膜肽。

Antennapedia Peptide(Synonyms: 黑腹果蝇触足肽)

Antennapedia Peptide Chemical Structure

CAS No. : 188842-14-0

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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Antennapedia Peptide 的其他形式现货产品:

Antennapedia Peptide(TFA)

生物活性

Antennapedia Peptide is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of Cell-penetrating peptides.

体外研究
(In Vitro)

Antennapedia (Antp)-SMCC-cytochrome c conjugate (5 μg/mL) activates caspase-dependent apoptosis of HeLa cells. The Antp-SMCC-cytochrome c conjugate reduces the clonogenic survival of Hela cells, and inhibits clonogenic survival[1]. ANTP-SmacN7 fusion protein can transduce and accumulate in cells, while SmacN7 alone cannot. ANTP-SmacN7 fusion proteins have a radiation-sensitising effect on EC109 cells. ANTP-SmacN7 combined with radiation does not promote further increases in caspase-3 protein expression, it increases the levels of cleaved caspase-3[2].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

2246.80

Formula

FI2K4NW2
CAS 号

188842-14-0
Sequence

Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys
Sequence Shortening

RQIKIWFQNRRMKWKK
中文名称

黑腹果蝇触足肽
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Imesch P, et al. Conjugates of cytochrome c and antennapedia peptide activate apoptosis and inhibit proliferation of HeLa cancer cells. Exp Ther Med. 2013 Sep;6(3):786-790. Epub 2013 Jul 4.

    [2]. Du LQ, et al. Radiation-sensitising effects of antennapedia proteins (ANTP)-SmacN7 on tumour cells. Int J Mol Sci. 2013 Dec 11;14(12):24087-96.

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Antennapedia Peptide(TFA)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Antennapedia Peptide(TFA)  纯度: 99.09%

Antennapedia Peptide TFA 是一种来自 Antennapedia 的含 16 个氨基酸的多肽 (RQIKIWFQNRRMKWKK)。

Antennapedia Peptide(TFA)

Antennapedia Peptide(TFA) Chemical Structure

规格 价格 是否有货 数量
1 mg ￥1400 In-stock
5 mg ￥3600 In-stock
10 mg ￥5760 In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Antennapedia Peptide(TFA) 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Antennapedia Peptide is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of Cell-penetrating peptides.

体外研究
(In Vitro)

Antennapedia Peptide TFA is a 16 amino acid peptide (RQIKIWFQNRRMKWKK). The DNA binding domain of the Drosophila transcription factor (Antennapedia), a 60 amino acid protein, is rapidly taken up by cells and has been fused to selected antigens to enhance their immunogenicity. A 16 amino acid peptide Antennapedia Peptide TFA from Antennapedia can facilitate the cytoplasmic uptake of cytotoxic T lymphocyte epitope 9-mer peptides[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

2360.82

Formula

C104H168N34O20S.C2HF3O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Protect from light, stored under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶解性数据
In Vitro: 

H2O : 100 mg/mL (42.36 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.4236 mL 2.1179 mL 4.2358 mL
5 mM 0.0847 mL 0.4236 mL 0.8472 mL
10 mM 0.0424 mL 0.2118 mL 0.4236 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Pietersz GA, et al. A 16-mer peptide (RQIKIWFQNRRMKWKK) from antennapedia preferentially targets the Class I pathway. Vaccine. 2001 Jan 8;19(11-12):1397-405.

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(Cys-Antennapedia Homeobox (43-58) amide)-(Cys-FLAG-Cofilin (1-13) (human, mouse, porcine, rat)) 编码

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名称 (Cys-Antennapedia Homeobox (43-58) amide)-(Cys-FLAG-Cofilin (1-13) (human, mouse, porcine, rat))
编码
别名 (Cys-Antennapedia Homeobox (43-58) amide)-(Cys-FLAG-Cofilin (1-13) (human, mouse, porcine, rat))
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） (H-CRQIKIWFQNRRMKWKK-NH2)A(H-CDYKDDDDKMASGVAVSDGVIK-OH)B
序列（三字母缩写） (Cys-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-NH2)A(Cys-Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys-Met-Ala-Ser-Gly-Val-Ala-Val-Ser-Asp-Gly-Val-Ile-Lys )B
基本描述
溶解度
分子量 0
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents (Cys-Antennapedia Homeobox (43-58) amide)-(Cys-FLAG-Cofilin (1-13) (human, mouse, porcine, rat)) 编码
Figures (Cys-Antennapedia Homeobox (43-58) amide)-(Cys-FLAG-Cofilin (1-13) (human, mouse, porcine, rat)) 编码
Reference
C端
N端
化学桥

多肽定制Cys(NPys)-Antennapedia Homeobox (43-58) amide 编码 [220337-24-6]

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上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称 Cys(NPys)-Antennapedia Homeobox (43-58) amide
编码 [220337-24-6]
别名 Cys(NPys)-Antennapedia Homeobox (43-58) amide
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） Cys(NPys)-RQIKIWFQNRRMKWKK-NH2
序列（三字母缩写） Cys(NPys)-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-NH2
基本描述
溶解度
分子量 0
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Cys(NPys)-Antennapedia Homeobox (43-58) amide 编码 [220337-24-6]
Figures Cys(NPys)-Antennapedia Homeobox (43-58) amide 编码 [220337-24-6]
Reference
C端
N端
化学桥