标签归档：bodipy

BODIPY aminoacetaldehyde(Synonyms: BAAA)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

BODIPY aminoacetaldehyde (Synonyms: BAAA)

BODIPY aminoacetaldehyde (BAAA) 是一种鼠类和人醛脱氢酶 (ALDH) 的荧光底物。BODIPY aminoacetaldehyde 由结合到 BODIPY 荧光染料上的氨基乙醛部分组成，可用于标记干细胞。

BODIPY aminoacetaldehyde(Synonyms: BAAA)

BODIPY aminoacetaldehyde Chemical Structure

CAS No. : 247069-94-9

规格 价格 是否有货
5 mg ￥15500 询问价格 & 货期
10 mg ￥25000 询问价格 & 货期

* Please select Quantity before adding items.

生物活性

BODIPY aminoacetaldehyde (BAAA) is a fluorescent substrate for both murine and human aldehyde dehydrogenase (ALDH). BODIPY aminoacetaldehyde consists of an aminoacetaldehyde moiety bonded to the BODIPY fluorochrome and can be used to label stem cells[1].

体外研究
(In Vitro)

When combined with inhibition of multidrug resistance, a population termed the SSCloALDHbr population could be readily fractionated from umbilical cord blood (UCB) mononuclear cells on the basis of high BODIPY aminoacetaldehyde (BAAA) staining intensity and low orthogonal light scattering[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

333.14

Formula

C16H18BF2N3O2
CAS 号

247069-94-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. R W Storms, et al. Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9118-23.

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Py-BODIPY-NHS ester

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Py-BODIPY-NHS ester  纯度: 98.98%

Py-BODIPY-NHS ester 是一种细胞渗透性荧光能量转移探针。Py-BODIPY-NHS ester 示踪剂具有很强的细胞结合力，是 MET 激酶的最佳选择。活细胞能量转移技术可对细胞内激酶靶点结合进行广泛的定量分析。

Py-BODIPY-NHS ester

Py-BODIPY-NHS ester Chemical Structure

CAS No. : 201998-61-0

规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ￥5280 In-stock
5 mg ￥4800 In-stock
10 mg ￥7800 In-stock
50 mg ￥21000 In-stock
100 mg ￥30000 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Py-BODIPY-NHS ester 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • Kinase Inhibitor Library
  • Anti-Cancer Compound Library

生物活性

Py-BODIPY-NHS ester is a cell-permeable and fluorescent energy transfer probe. Py-BODIPY-NHS ester tracer yields strong cellular engagement and proves to be optimal for MET kinase. The live-cell energy transfer technique can perform a broad-coverage, quantitative analysis of intracellular kinase target engagement[1][2].

体外研究
(In Vitro)

Triphenylphosphonium-fluorochromes (TPP-fluorochromes) are a new class of spectrally variable, mitochondrially targeted probes. NanoBRET 590 SE (compound 2b) is synthesized by reacting the TPP-amine with NHS esters of BODIPY red[3].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

426.18

Formula

C20H17BF2N4O4
CAS 号

201998-61-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro: 

DMSO : 125 mg/mL (293.30 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.3464 mL 11.7321 mL 23.4643 mL
5 mM 0.4693 mL 2.3464 mL 4.6929 mL
10 mM 0.2346 mL 1.1732 mL 2.3464 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂： 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (4.88 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (4.88 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂： 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.88 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (4.88 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
*以上所有助溶剂都可在 上海金畔生物科技有限公司 网站选购。
参考文献

  • [1]. Vasta JD, et al. Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of CellularATP on Target Engagement. Cell Chem Biol. 2018 Feb 15;25(2):206-214.e11.

    [2]. Robers MB, et al. Quantitative, Real-Time Measurements of Intracellular Target Engagement Using Energy Transfer. Methods Mol Biol. 2019;1888:45-71.

    [3]. Yuan H, et al. Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria. Chem Commun (Camb). 2013 Nov 14;49(88):10361-3.

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BODIPY 581/591 C11

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

BODIPY 581/591 C11 

C11-BODIPY581/591 是脂质氧化 (lipid oxidation) 的荧光比值探针。C11-BODIPY581/591 常用于评价模型膜系统和活细胞中的脂质过氧化和抗氧化作用。C11-BODIPY581/591 是用于铁死亡研究的常用手段。

BODIPY 581/591 C11

BODIPY 581/591 C11 Chemical Structure

CAS No. : 217075-36-0

规格 价格 是否有货
1 mg ￥3600 询问价格 & 货期
5 mg ￥10800 询问价格 & 货期

* Please select Quantity before adding items.

生物活性

C11-BODIPY581/591 is a fluorescent ratio-probe of lipid oxidation. C11-BODIPY581/591 is often used for indexing lipid peroxidation and antioxidant efficacy in model membrane systems and living cells. C11-BODIPY581/591 is applied in the quantitation of ferroptosis[1].

体外研究
(In Vitro)

C11-BODIPY581/591 can easily enter membranes and exhibits good spectral separation of the nonoxidized (595 nm) and oxidized (520 nm) forms[1].
Stock solutions of C11 BODIPY581/591 are made by dissolving 1 mg in 20 mM organic solvent.
Cells are labeled in DMEM or PBS with 1-20 μM C11-BODIPY581/591 at 37°C, 30 min before the experiment.
Alternatively, cells are incubated in DMEM with 1-10 μM preoxidized C11-BODIPY581/591.

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

504.42

Formula

C30H35BF2N2O2
CAS 号

217075-36-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Gregor P C Drummen, et al. C11-BODIPY(581/591), an oxidation-sensitive fluorescent lipid peroxidation probe: (micro)spectroscopic characterization and validation of methodology. Free Radic Biol Med. 2002 Aug 15;33(4):473-90.

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meso-CF3-BODIPY 2(Synonyms: CF3-substituted Tetramethyl BODIPY)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

meso-CF3-BODIPY 2 (Synonyms: CF3-substituted Tetramethyl BODIPY)

meso-CF3-BODIPY 2 (CF3-substituted Tetramethyl BODIPY) 是一种荧光染料，吸收波长 (λabs) 为 553 nm，发射波长 (λem) 为 622 nm。meso-CF3-BODIPY 2 可用于标记试剂和光动力疗法。

meso-CF3-BODIPY 2(Synonyms: CF3-substituted Tetramethyl BODIPY)

meso-CF3-BODIPY 2 Chemical Structure

CAS No. : 1642327-22-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

meso-CF3-BODIPY 2 (CF3-substituted Tetramethyl BODIPY) is a fluorescent dye with the absorption wavelength (λabs) of 553 nm and emission wavelength (λem) of 622 nm. meso-CF3-BODIPY 2 can be used in labeling reagents and photodynamic therapy[1][2].

体外研究
(In Vitro)

meso-CF3-BODIPY 2 have significant utility in a variety of applications, such as labeling reagents, organic photovoltaics, organic light-emitting diodes, photodynamic therapy[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

316.08

Formula

C14H14BF5N2
CAS 号

1642327-22-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Sun Y, et, al. Thieno[3,2-b]thiophene fused BODIPYs: synthesis, near-infrared luminescence and photosensitive properties. Organic & Biomolecular Chemistry. 2019; 17(14): 3617-3622.

    [2]. Jiang XD, et, al. Synthesis of meso-CF3-Substituted BODIPY Compounds with Redshifted Absorption. European Journal of Organic Chemistry. 2017 Sep 15; 2017(34): 5074-5079.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

meso-CF3-BODIPY 2(Synonyms: CF3-substituted Tetramethyl BODIPY)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

meso-CF3-BODIPY 2 (Synonyms: CF3-substituted Tetramethyl BODIPY)

meso-CF3-BODIPY 2 (CF3-substituted Tetramethyl BODIPY) 是一种荧光染料，吸收波长 (λabs) 为 553 nm，发射波长 (λem) 为 622 nm。meso-CF3-BODIPY 2 可用于标记试剂和光动力疗法。

meso-CF3-BODIPY 2(Synonyms: CF3-substituted Tetramethyl BODIPY)

meso-CF3-BODIPY 2 Chemical Structure

CAS No. : 1642327-22-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

meso-CF3-BODIPY 2 (CF3-substituted Tetramethyl BODIPY) is a fluorescent dye with the absorption wavelength (λabs) of 553 nm and emission wavelength (λem) of 622 nm. meso-CF3-BODIPY 2 can be used in labeling reagents and photodynamic therapy[1][2].

体外研究
(In Vitro)

meso-CF3-BODIPY 2 have significant utility in a variety of applications, such as labeling reagents, organic photovoltaics, organic light-emitting diodes, photodynamic therapy[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

316.08

Formula

C14H14BF5N2
CAS 号

1642327-22-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Sun Y, et, al. Thieno[3,2-b]thiophene fused BODIPYs: synthesis, near-infrared luminescence and photosensitive properties. Organic & Biomolecular Chemistry. 2019; 17(14): 3617-3622.

    [2]. Jiang XD, et, al. Synthesis of meso-CF3-Substituted BODIPY Compounds with Redshifted Absorption. European Journal of Organic Chemistry. 2017 Sep 15; 2017(34): 5074-5079.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

meso-CF3-BODIPY 2(Synonyms: CF3-substituted Tetramethyl BODIPY)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

meso-CF3-BODIPY 2 (Synonyms: CF3-substituted Tetramethyl BODIPY)

meso-CF3-BODIPY 2 (CF3-substituted Tetramethyl BODIPY) 是一种荧光染料，吸收波长 (λabs) 为 553 nm，发射波长 (λem) 为 622 nm。meso-CF3-BODIPY 2 可用于标记试剂和光动力疗法。

meso-CF3-BODIPY 2(Synonyms: CF3-substituted Tetramethyl BODIPY)

meso-CF3-BODIPY 2 Chemical Structure

CAS No. : 1642327-22-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

meso-CF3-BODIPY 2 (CF3-substituted Tetramethyl BODIPY) is a fluorescent dye with the absorption wavelength (λabs) of 553 nm and emission wavelength (λem) of 622 nm. meso-CF3-BODIPY 2 can be used in labeling reagents and photodynamic therapy[1][2].

体外研究
(In Vitro)

meso-CF3-BODIPY 2 have significant utility in a variety of applications, such as labeling reagents, organic photovoltaics, organic light-emitting diodes, photodynamic therapy[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

316.08

Formula

C14H14BF5N2
CAS 号

1642327-22-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Sun Y, et, al. Thieno[3,2-b]thiophene fused BODIPYs: synthesis, near-infrared luminescence and photosensitive properties. Organic & Biomolecular Chemistry. 2019; 17(14): 3617-3622.

    [2]. Jiang XD, et, al. Synthesis of meso-CF3-Substituted BODIPY Compounds with Redshifted Absorption. European Journal of Organic Chemistry. 2017 Sep 15; 2017(34): 5074-5079.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务