标签归档：cpg

Carboxypeptidase G2 (CPG2) Inhibitor(Synonyms: CPG2 Inhibitor)

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Carboxypeptidase G2 (CPG2) Inhibitor (Synonyms: CPG2 Inhibitor) 纯度: 98.14%

Carboxypeptidase G2 (CPG2) Inhibitor是羧肽酶G2（CPG2）抑制剂，具有抗癌活性。

Carboxypeptidase G2 (CPG2) Inhibitor(Synonyms: CPG2 Inhibitor)

Carboxypeptidase G2 (CPG2) Inhibitor Chemical Structure

CAS No. : 192203-60-4

规格 价格 是否有货 数量
50 mg ￥7440 In-stock
100 mg ￥10323 In-stock
200 mg   询价  
500 mg   询价  

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Carboxypeptidase G2 (CPG2) Inhibitor 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • Metabolism/Protease Compound Library
  • Anti-Cancer Compound Library
  • Peptidomimetic Library

生物活性

Carboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents.

分子量

313.33

Formula

C13H15NO6S
CAS 号

192203-60-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

H2O : 1.43 mg/mL (4.56 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.1915 mL 15.9576 mL 31.9152 mL
5 mM — — —
10 mM — — —

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Khan, Tariq H.; Eno-Amooquaye, Ebun A.; Searle, Frances et al. Novel Inhibitors of Carboxypeptidase G2 (CPG2): Potential Use in Antibody-Directed Enzyme Prodrug Therapy. Journal of Medicinal Chemistry (1999), 42(6), 951-956.

    [2]. Friedlos F, Lehouritis P, Ogilvie L et al. Attenuated Salmonella targets prodrug activating enzyme carboxypeptidase G2 to mouse melanoma and human breast and colon carcinomas for effective suicide gene therapy. Clin Cancer Res. 2008 Jul 1;14(13):4259-66.

    [3]. Schepelmann S, Ogilvie LM, Hedley D et al. Suicide gene therapy of human colon carcinoma xenografts using an armed oncolytic adenovirus expressing carboxypeptidase G2. Cancer Res. 2007 May 15;67(10):4949-55.

    [4]. Schepelmann S, Hallenbeck P, Ogilvie LM et al. Systemic gene-directed enzyme prodrug therapy of hepatocellular carcinoma using a targeted adenovirus armed with carboxypeptidase G2. Cancer Res. 2005 Jun 15;65(12):5003-8.

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