标签归档：cypmpo

CYPMPO

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

CYPMPO 

CYPMPO 是一种自旋捕捉剂。CYPMPO 是一种环状 DEPMPO 型硝酮，用于评估对羟基和超氧自由基的自旋捕获能力。抗氧化和抗肿瘤活性。

CYPMPO

CYPMPO Chemical Structure

CAS No. : 934182-09-9

规格 是否有货
1 mg 询价

* Please select Quantity before adding items.

生物活性

CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor activity[1].

体外研究
(In Vitro)

DMPO is often used as a spin trapping agent to detect oxygen-centered radicals. CYPMPO has a larger reaction rate constant with superoxide anion than DMPO and the superoxide adduct of CYPMPO is more stable than that of DMPO. CYPMPO (2.5 mM) acts as a spin-trap agent[2].
CYPMPO, a spin-trap, a cyclic DEPMPO-like nitrone trap, may provide new free radical information when used with mitochondria. CYPMPO has the preferential quality of having minimal mitochondrial toxicity at concentrations required for radical detection[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

247.23

Formula

C10H18NO4P
CAS 号

934182-09-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Masato Kamibayashi, et al. Synthesis and characterization of a practically better DEPMPO-type spin trap, 5-(2,2-dimethyl-1,3-propoxy cyclophosphoryl)-5-methyl-1-pyrroline N-oxide (CYPMPO). Free Radic Res. 2006 Nov;40(11):1166-72.

    [2]. Ryohei Umeda, et al. Direct free radical scavenging effects of water-soluble HMG-CoA reductase inhibitors. J Clin Biochem Nutr. 2019 Jan;64(1):20-26.

    [3]. Matsuzaki S, et al. Identification of mitochondrial electron transport chain-mediated NADH radical formation by EPR spin-trapping techniques. Biochemistry 2011, 50, 50, 10792-10803.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

CYPMPO

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

CYPMPO 

CYPMPO 是一种自旋捕捉剂。CYPMPO 是一种环状 DEPMPO 型硝酮，用于评估对羟基和超氧自由基的自旋捕获能力。抗氧化和抗肿瘤活性。

CYPMPO

CYPMPO Chemical Structure

CAS No. : 934182-09-9

规格 是否有货
1 mg 询价

* Please select Quantity before adding items.

生物活性

CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor activity[1].

体外研究
(In Vitro)

DMPO is often used as a spin trapping agent to detect oxygen-centered radicals. CYPMPO has a larger reaction rate constant with superoxide anion than DMPO and the superoxide adduct of CYPMPO is more stable than that of DMPO. CYPMPO (2.5 mM) acts as a spin-trap agent[2].
CYPMPO, a spin-trap, a cyclic DEPMPO-like nitrone trap, may provide new free radical information when used with mitochondria. CYPMPO has the preferential quality of having minimal mitochondrial toxicity at concentrations required for radical detection[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

247.23

Formula

C10H18NO4P
CAS 号

934182-09-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Masato Kamibayashi, et al. Synthesis and characterization of a practically better DEPMPO-type spin trap, 5-(2,2-dimethyl-1,3-propoxy cyclophosphoryl)-5-methyl-1-pyrroline N-oxide (CYPMPO). Free Radic Res. 2006 Nov;40(11):1166-72.

    [2]. Ryohei Umeda, et al. Direct free radical scavenging effects of water-soluble HMG-CoA reductase inhibitors. J Clin Biochem Nutr. 2019 Jan;64(1):20-26.

    [3]. Matsuzaki S, et al. Identification of mitochondrial electron transport chain-mediated NADH radical formation by EPR spin-trapping techniques. Biochemistry 2011, 50, 50, 10792-10803.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

CYPMPO

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

CYPMPO 

CYPMPO 是一种自旋捕捉剂。CYPMPO 是一种环状 DEPMPO 型硝酮，用于评估对羟基和超氧自由基的自旋捕获能力。抗氧化和抗肿瘤活性。

CYPMPO

CYPMPO Chemical Structure

CAS No. : 934182-09-9

规格 是否有货
1 mg 询价

* Please select Quantity before adding items.

生物活性

CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor activity[1].

体外研究
(In Vitro)

DMPO is often used as a spin trapping agent to detect oxygen-centered radicals. CYPMPO has a larger reaction rate constant with superoxide anion than DMPO and the superoxide adduct of CYPMPO is more stable than that of DMPO. CYPMPO (2.5 mM) acts as a spin-trap agent[2].
CYPMPO, a spin-trap, a cyclic DEPMPO-like nitrone trap, may provide new free radical information when used with mitochondria. CYPMPO has the preferential quality of having minimal mitochondrial toxicity at concentrations required for radical detection[3].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

247.23

Formula

C10H18NO4P
CAS 号

934182-09-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Masato Kamibayashi, et al. Synthesis and characterization of a practically better DEPMPO-type spin trap, 5-(2,2-dimethyl-1,3-propoxy cyclophosphoryl)-5-methyl-1-pyrroline N-oxide (CYPMPO). Free Radic Res. 2006 Nov;40(11):1166-72.

    [2]. Ryohei Umeda, et al. Direct free radical scavenging effects of water-soluble HMG-CoA reductase inhibitors. J Clin Biochem Nutr. 2019 Jan;64(1):20-26.

    [3]. Matsuzaki S, et al. Identification of mitochondrial electron transport chain-mediated NADH radical formation by EPR spin-trapping techniques. Biochemistry 2011, 50, 50, 10792-10803.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务