标签归档：desthiobiotin

Desthiobiotin-PEG4-acid

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Desthiobiotin-PEG4-acid 

Desthiobiotin-PEG4-acid 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Desthiobiotin-PEG4-acid

Desthiobiotin-PEG4-acid Chemical Structure

规格 价格 是否有货
50 mg ￥4800 询问价格 & 货期
100 mg ￥7600 询问价格 & 货期
250 mg ￥14000 询问价格 & 货期

* Please select Quantity before adding items.

生物活性

Desthiobiotin-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

461.55

Formula

C21H39N3O8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Desthiobiotin PEG NHS Cat. No. PG2-DSBNS-5k 5000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Desthiobiotin PEG NHS

Cat. No. PG2-DSBNS-5k
Specification 5000 Da
Unit Size 5 mg
Price $325.00

Qty Add to Cart

Desthiobiotin PEG NHS is one of Nanocs’ reactive desthiobiotin PEG crosslinkers that can react with primary amine groups. Desthiobiotin is a modified version of biotin. Compared to biotin, desthiobiotin binds to streptavidin, avidin or neutraviain with lower affinity and thus it can be eluted under milder conditions (i.e., by competitive displacement with regular, free biotin). As such, desthiobiotin reagent is a useful alternative to Biotin for avidin-biotin techniques in which nondenaturing elution of the labeled proteins is desired. Succinimidyl ester (NHS) reacts specifically and efficiently with primary amine group (-NH2) at alkaline pH to form a stable amide bond. Reaction between NHS and amine allows quick and efficient conjugation of desthiobiotin tag to proteins, antibodies and other biomolecules. Resulted desthibiotin conjugates can be used for bioassay development, biomolecule separation and purification. PEG linker between desthiobiotin and maleimide offers better water solubility, reduced steric hindrance and enhanced stability.

Physical Properties:

  • Off-white/white solid;
  • Soluble in water, DMSO or DMF;
  • Reactive group: Succinimidyl ester (NHS);
  • Reactive toward: Primary amine (-NH2).

Storage Conditions:

  • Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Tags: Desthiobiotin PEG,

Desthiobiotin PEG NHS Cat. No. PG2-DSBNS-3k 3400 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Desthiobiotin PEG NHS

Cat. No. PG2-DSBNS-3k
Specification 3400 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Desthiobiotin PEG NHS is one of Nanocs’ reactive desthiobiotin PEG crosslinkers that can react with primary amine groups. Desthiobiotin is a modified version of biotin. Compared to biotin, desthiobiotin binds to streptavidin, avidin or neutraviain with lower affinity and thus it can be eluted under milder conditions (i.e., by competitive displacement with regular, free biotin). As such, desthiobiotin reagent is a useful alternative to Biotin for avidin-biotin techniques in which nondenaturing elution of the labeled proteins is desired. Succinimidyl ester (NHS) reacts specifically and efficiently with primary amine group (-NH2) at alkaline pH to form a stable amide bond. Reaction between NHS and amine allows quick and efficient conjugation of desthiobiotin tag to proteins, antibodies and other biomolecules. Resulted desthibiotin conjugates can be used for bioassay development, biomolecule separation and purification. PEG linker between desthiobiotin and maleimide offers better water solubility, reduced steric hindrance and enhanced stability.

Physical Properties:

  • Off-white/white solid;
  • Soluble in water, DMSO or DMF;
  • Reactive group: Succinimidyl ester (NHS);
  • Reactive toward: Primary amine (-NH2).

Storage Conditions:

  • Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Tags: Desthiobiotin PEG,

Desthiobiotin PEG NHS Cat. No. PG2-DSBNS-2k 2000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Desthiobiotin PEG NHS

Cat. No. PG2-DSBNS-2k
Specification 2000 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Desthiobiotin PEG NHS is one of Nanocs’ reactive desthiobiotin PEG crosslinkers that can react with primary amine groups. Desthiobiotin is a modified version of biotin. Compared to biotin, desthiobiotin binds to streptavidin, avidin or neutraviain with lower affinity and thus it can be eluted under milder conditions (i.e., by competitive displacement with regular, free biotin). As such, desthiobiotin reagent is a useful alternative to Biotin for avidin-biotin techniques in which nondenaturing elution of the labeled proteins is desired. Succinimidyl ester (NHS) reacts specifically and efficiently with primary amine group (-NH2) at alkaline pH to form a stable amide bond. Reaction between NHS and amine allows quick and efficient conjugation of desthiobiotin tag to proteins, antibodies and other biomolecules. Resulted desthibiotin conjugates can be used for bioassay development, biomolecule separation and purification. PEG linker between desthiobiotin and maleimide offers better water solubility, reduced steric hindrance and enhanced stability.

Physical Properties:

  • Off-white/white solid;
  • Soluble in water, DMSO or DMF;
  • Reactive group: Succinimidyl ester (NHS);
  • Reactive toward: Primary amine (-NH2).

Storage Conditions:

  • Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Related Products
PG2-AMDSB-5k , Desthiobiotin PEG amine

Tags: Desthiobiotin PEG,

Desthiobiotin PEG Maleimide Cat. No. PG2-DSBML-5k 5000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Desthiobiotin PEG Maleimide

Cat. No. PG2-DSBML-5k
Specification 5000 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Desthiobiotin PEG Maleimide:

Desthiobiotin PEG Maleimide is one of Nanocs’ reactive desthiobiotin PEG crosslinkers that can react with thiol (-SH) groups. Maleimide reacts with thiol/sulfhydryl group at neutral pH quckily and efficiently. Reaction between maleimide and thiol allows conjugation of desthiobiotin tag to proteins, antibodies, peptides or nucleic acids with high efficiency. Desthiobiotin is a modified version of biotin. Compared to biotin, desthiobiotin binds to streptavidin, avidin and other biotin-binding proteins with lower affinity and it can be eluted from binding complex under much milder conditions (i.e., by competitive displacement with regular, free biotin). As such, desthiobiotin reagent is a useful alternative to Biotin for avidin-biotin techniques in which nondenaturing elution of the labeled proteins is desired. PEG linker between desthiobiotin and maleimide offers better water solubility, less steric hindrance and enhanced stability.

Physical Properties:

  • Off-white/white solid;
  • Soluble in water, DMSO or DMF;
  • Reactive group: Maleimide;
  • Reactive to: Thiol (-SH);

Storage Conditions:

  • Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Tags: Desthiobiotin PEG,

Maleimide PEG Desthiobiotin Cat. No. PG2-DSBML-3k 3400 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Maleimide PEG Desthiobiotin

Cat. No. PG2-DSBML-3k
Specification 3400 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Desthiobiotin PEG Maleimide:

Desthiobiotin PEG Maleimide is one of Nanocs’ reactive desthiobiotin PEG crosslinkers that can react with thiol (-SH) groups. Maleimide reacts with thiol/sulfhydryl group at neutral pH quckily and efficiently. Reaction between maleimide and thiol allows conjugation of desthiobiotin tag to proteins, antibodies, peptides or nucleic acids with high efficiency. Desthiobiotin is a modified version of biotin. Compared to biotin, desthiobiotin binds to streptavidin, avidin and other biotin-binding proteins with lower affinity and it can be eluted from binding complex under much milder conditions (i.e., by competitive displacement with regular, free biotin). As such, desthiobiotin reagent is a useful alternative to Biotin for avidin-biotin techniques in which nondenaturing elution of the labeled proteins is desired. PEG linker between desthiobiotin and maleimide offers better water solubility, less steric hindrance and enhanced stability.

Physical Properties:

  • Off-white/white solid;
  • Soluble in water, DMSO or DMF;
  • Reactive group: Maleimide;
  • Reactive to: Thiol (-SH);

Storage Conditions:

  • Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Tags: Desthiobiotin PEG,

Desthiobiotin PEG Maleimide Cat. No. PG2-DSBML-2k 2000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Desthiobiotin PEG Maleimide

Cat. No. PG2-DSBML-2k
Specification 2000 Da
Unit Size 5 mg
Price $425.00

Qty Add to Cart

Desthiobiotin PEG Maleimide:

Desthiobiotin PEG Maleimide is one of Nanocs’ reactive desthiobiotin PEG crosslinkers that can react with thiol (-SH) groups. Maleimide reacts with thiol/sulfhydryl group at neutral pH quckily and efficiently. Reaction between maleimide and thiol allows conjugation of desthiobiotin tag to proteins, antibodies, peptides or nucleic acids with high efficiency. Desthiobiotin is a modified version of biotin. Compared to biotin, desthiobiotin binds to streptavidin, avidin and other biotin-binding proteins with lower affinity and it can be eluted from binding complex under much milder conditions (i.e., by competitive displacement with regular, free biotin). As such, desthiobiotin reagent is a useful alternative to Biotin for avidin-biotin techniques in which nondenaturing elution of the labeled proteins is desired. PEG linker between desthiobiotin and maleimide offers better water solubility, less steric hindrance and enhanced stability.

Physical Properties:

  • Off-white/white solid;
  • Soluble in water, DMSO or DMF;
  • Reactive group: Maleimide;
  • Reactive to: Thiol (-SH);

Storage Conditions:

  • Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Related Products
PG2-AMDSB-5k , Desthiobiotin PEG amine

Tags: Desthiobiotin PEG,

Desthiobiotin PEG amine Cat. No. PG2-AMDSB-5k 5000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Desthiobiotin PEG amine

Cat. No. PG2-AMDSB-5k
Specification 5000 Da
Unit Size 5 mg
Price $325.00

Qty Add to Cart

Synonyn:Desthiobiotin PEG NH2, DSB-PEG-NH2, NH2 PEG Desthiobiotin, Amino PEG Desthiobiotin

Desthiobiotin PEG amine (DSB-PEG-NH2) is one of Nanocs’ desthiobiotin PEG crosslinkers that have a reactive primary amine group on one PEG terminus and a desthiobiotin tag on the other PEG end. Desthiobiotin is a modified version of biotin. Compared to biotin, desthiobiotin binds to streptavidin, avidin and other biotin-binding proteins with lower affinity and it can be eluted from binding complex with much more gental conditions (i.e., by competitive displacement with regular, free biotin). As such, desthiobiotin reagent is a useful alternative to Biotin for avidin-biotin techniques in which nondenaturing elution of the labeled proteins is desired. Amine functionalized desthiobiotin can react with a number of amine reactive groups such as succinimidyl ester, carboxylic acid, aldehyde, etc. Reaction between amine and other groups allows quick and efficient conjugation of desthiobiotin tag to proteins, antibodies and other biomolecules. PEG linker between desthiobiotin and amine group offers better water solubility, reduced steric hindrance and enhanced reactivity.

Physical Properties:

  • Off-white/white solid;
  • Soluble in aqueous buffer, DMSO or DMF;
  • Reactive group: Primary amine (-NH2);
  • Reactive to: NHS, aldehyde, COOH, etc.;

Storage Conditions:

  • Store at <-20 0C. Desiccate. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Related Products
PG2-DSBNS-2k , Desthiobiotin PEG NHS
PG2-DSBML-2k , Desthiobiotin PEG Maleimide
PG2-DSBTH-5k , Desthiobiotin PEG thiol
PG2-DBDSB-5k , Desthiobiotin PEG DBCO

Tags: Desthiobiotin PEG,

Desthiobiotin PEG thiol Cat. No. PG2-DSBTH-5k 5000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Desthiobiotin PEG thiol

Cat. No. PG2-DSBTH-5k
Specification 5000 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Desthiobiotin PEG Thiol:

Desthiobiotin PEG Thiol is one of Nanocs’ thiolated desthiobiotin PEG derivatives that can bind to gold particle surface with high affinity. It can also react with a number of thiol reactive groups such as maleimide, iodoacetyl and pyridyldithio, etc. Reactions bewteen thiol and gold or other groups allows conjugation of desthiobiotin tag to targeted molecule or materials substrates quickly and efficiently. Resulted desthiobiotin can be used to bind to avdidin or streptavidin. PEG linker between thiol and desthiobiotin offers better water solubility, reduced steric hindrance and ehanced reactivity.

Physical Properties:

  • Off-white/white solid;
  • Soluble in aqeous solution, DMSO or DMF;
  • Reactive group: Thiol (-SH);
  • Reactive to: Maleimide, Iodoacetyl, Pyridyldithio, etc.;

Storage Conditions:

  • Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Related Products
PG2-AMDSB-5k , Desthiobiotin PEG amine

Tags: Desthiobiotin PEG,

Desthiobiotin PEG azide Cat. No. PG2-AZDSB-5k 5000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Desthiobiotin PEG azide

Cat. No. PG2-AZDSB-5k
Specification 5000 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Desthiobiotin PEG Azide:

Desthiobiotin PEG Azide is one of Nanocs’ reactive desthiobiotin derivatives. Azide is a commonly used click chemistry functional group that can react with alkyne catalyzed by copper ion. It can also react with strain-promoted cyclooctyne such as DBCO spontaneously without need any catalyst. Reaction between azide and alkyne allows attachment of destionbiotin tag to targeted molecules or material substrates with high efficiency. Resulted desthiobiotin can bind to avidin or streptavidin, and it can be eluted from avidin/streptavidin complex under milder conditions. PEG linker between azide and desthiobiotin offers higher water solubility, reduced steric hindrance and enhanced activity.

Physical Properties:

  • Off-white/white solid;
  • Soluble in aqeous solution, DMSO or DMF;
  • Reactive group: Azide (-N3);
  • Reactive to: Alkye, DBCO, etc.;

Storage Conditions:

  • Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Tags: Desthiobiotin PEG,

Desthiobiotin PEG Alkyne Cat. No. PG2-AKDSB-5k 5000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Desthiobiotin PEG Alkyne

Cat. No. PG2-AKDSB-5k
Specification 5000 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Desthiobiotin PEG Alkyne:

Alkyne PEG Desthiobiotin is one of click chemistry reactive desthiobiotin derivatives offered by Nanocs. Alkyne reacts with azide group through Huisgen 1,3-Dipolar cycloaddition to form a stable triazole linkage. Reaction of alkyne and azide proceeds well in aqueous solution catalyzed by copper (I) ion catalyst. This reaction allows attachment of desthiobiotin tag to the targeted molecule or material substrates quickly and efficiently. PEG linker between alkyne and desthiobiotin provides higher water solubility, less steric hindrance and enhanced reactivity.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;
  • Reactive group: Alkyne;
  • Reactive to: Azide;

Storage Conditions:

  • Store at -20 0C.
Documents
  • SDS
  • DataSheet

Tags: Desthiobiotin PEG,

Desthiobiotin PEG DBCO Cat. No. PG2-DBDSB-5k 5000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Desthiobiotin PEG DBCO

Cat. No. PG2-DBDSB-5k
Specification 5000 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Desthiobiotin PEG DBCO:

DBCO PEG Desthiobiotin is a reactive Desthiobiotin PEG derivative offered by Nanocs. DBCO (Dibenzocyclooctyne) is a commonly used copper free click chemistry reagent that can react with azide group with high specificity. Reaction between DBCO and azide allows fast and efficient attachment of desthiobiotin to target molecules or materials. Resulted desthiobiotin conjugate is able to bind to avidin or streptavidin but it can be eluted from avidin or streptavidin complex under milder conditions. PEG linker between DBCO and desthiobiotin offers higher water solubility, less steric hindrance and better stability.

Physical Properties:

  • Off-white/white solid;
  • Soluble in aqueous solution, DMSO or DMF;
  • Reactive group: DBCO;
  • Reactive to: Azide;

Storage Conditions:

  • Store at -20 0C.
Documents
  • SDS
  • DataSheet

Related Products
PG2-AMDSB-5k , Desthiobiotin PEG amine

Tags: Desthiobiotin PEG,

Desthiobiotin PEG FITC Cat. No. PG2-DSBFC-5k 5000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Desthiobiotin PEG FITC

Cat. No. PG2-DSBFC-5k
Specification 5000 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Desthiobiotin PEG FITC:

Fluorescein PEG Desthiobiotin, also called Desthiobiotin PEG FITC, is a fluorescent Desthiobiotin PEG derivative offered by Nanocs. Desthiobiotin PEG FITC gives strong green fluorescence light upon excited at 495 nm. The maximum emission wavelength of product is around 515 nm. FITC labeled desthiobiotin PEG can be used to trace and detect binding of desthiobiotin to avidin, streptavidin or neutravidin with high sentivity. PEG linker between FITC and Desthiobiotin offers good water solubility, less steric hindrance and enhanced stability.

Physical Properties:

  • Yellow/orange solid;
  • Soluble in regular aqeous solution as well as most organic solvents;
  • Excitation/Emission wavelength: 495/515 nm;

Storage Conditions:

  • Store at -20 0C. Preotect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Tags: Desthiobiotin PEG,

Desthiobiotin PEG Amiooxy Cat. No. PG2-AODSB-5k 5000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Desthiobiotin PEG Amiooxy

Cat. No. PG2-AODSB-5k
Specification 5000 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Desthiobiotin PEG Aminooxy:

Aminooxy PEG Desthiobiotin is one of carbonyl reactive Desthiobiotin PEG derivatives from Nanocs that can be used to attach desthiobiotin tag to polysaccharides or glycoproteins with aldehyde or ketone groups. Reaction between aminooxy and carbonyl group forms a stable oxime bond that is more stable than schiff base formed between amino and carbonyl group. Aminooxy and carbonyl reaction allows covalent conjugation of desthiobiotin to periodate oxidized polysaccharides or glycoproteins. Resulted desthiobiotin tag can bind to avdin, neutravidin or streptavidin with high specificity but it can be eluted from avidin/streptavidin complex under milder conditions.

Physical Properties:

  • Off-white/white solid;
  • Soluble in aqueous solution, DMSO or DMF;
  • Reactive group: Aminooxy (-ONH2);
  • Reactive to: Aldehyde or ketone group from polysaccharides or glycoproteins;

Storage Conditions:

  • Store at -20 0C. Desiccate. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Tags: Desthiobiotin PEG,

Desthiobiotin PEG DSPE Cat. No. PG2-DSDSB-5k 5000 Da 5 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Desthiobiotin PEG DSPE

Cat. No. PG2-DSDSB-5k
Specification 5000 Da
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Desthiobiotin PEG DSPE:

DSPE PEG Desthiobiotin is one of Nanocs’ phospholipid PEG derivatives with a desthiobiotin tag. DSPE is an amphiphilic 18 carbon phospholipid existing in cell membranes and artificial liposomes. Desthiobiotin is a modified version of biotin. Compared to biotin, desthiobiotin binds to streptavidin, avidin or neutraviain with lower affinity and thus it can be eluted under milder conditions (i.e., by competitive displacement with regular, free biotin). As such, desthiobiotin reagent is a useful alternative to Biotin for avidin-biotin techniques in which nondenaturing elution of the labeled proteins is desired. DSPE modified PEG desthiobiotin has excellent amphiphilic property that can be incorporated into cell membranes, liposomes and other synthetic lipophilic nanoparticles. Resulted desthiobiotin can target avidin, streptavidin or neutravidin. PEG linker between DSPE and desthiobiotin tag offers better water solubility, less steric hindrance and enhanced stability.

Physical Properties:

  • Off-white/white solid;
  • Soluble in aqueous solution, DMSO or DMF;
  • Functional group: desthiobiotin, DSPE;
  • Reactive to: streptavidin, avidin;

Storage Conditions:

  • Store at -20 0C.
Documents
  • SDS
  • DataSheet

Tags: Desthiobiotin PEG,

DBCO-PEG4-Desthiobiotin

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

DBCO-PEG4-Desthiobiotin 

DBCO-PEG4-Desthiobiotin 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

DBCO-PEG4-Desthiobiotin

DBCO-PEG4-Desthiobiotin Chemical Structure

CAS No. : 2032788-37-5

规格 是否有货
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* Please select Quantity before adding items.

生物活性

DBCO-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

719.87

Formula

C39H53N5O8
CAS 号

2032788-37-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

N-Desthiobiotin-N-bis(PEG4-t-butyl ester)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

N-Desthiobiotin-N-bis(PEG4-t-butyl ester) 

N-Desthiobiotin-N-bis(PEG4-t-butyl ester) 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

N-Desthiobiotin-N-bis(PEG4-t-butyl ester)

N-Desthiobiotin-N-bis(PEG4-t-butyl ester) Chemical Structure

CAS No. : 2353409-60-4

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

N-Desthiobiotin-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

822.04

Formula

C40H75N3O14
CAS 号

2353409-60-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

N-Desthiobiotin-N-bis(PEG4-NHS ester)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

N-Desthiobiotin-N-bis(PEG4-NHS ester) 

N-Desthiobiotin-N-bis(PEG4-NHS ester) 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

N-Desthiobiotin-N-bis(PEG4-NHS ester)

N-Desthiobiotin-N-bis(PEG4-NHS ester) Chemical Structure

CAS No. : 2353409-61-5

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

N-Desthiobiotin-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

903.97

Formula

C40H65N5O18
CAS 号

2353409-61-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

N-Desthiobiotin-N-bis(PEG4-t-butyl ester)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

N-Desthiobiotin-N-bis(PEG4-t-butyl ester) 

N-Desthiobiotin-N-bis(PEG4-t-butyl ester) 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

N-Desthiobiotin-N-bis(PEG4-t-butyl ester)

N-Desthiobiotin-N-bis(PEG4-t-butyl ester) Chemical Structure

CAS No. : 2353409-60-4

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

N-Desthiobiotin-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

822.04

Formula

C40H75N3O14
CAS 号

2353409-60-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

N-Desthiobiotin-N-bis(PEG4-NHS ester)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

N-Desthiobiotin-N-bis(PEG4-NHS ester) 

N-Desthiobiotin-N-bis(PEG4-NHS ester) 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

N-Desthiobiotin-N-bis(PEG4-NHS ester)

N-Desthiobiotin-N-bis(PEG4-NHS ester) Chemical Structure

CAS No. : 2353409-61-5

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

N-Desthiobiotin-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

903.97

Formula

C40H65N5O18
CAS 号

2353409-61-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务