上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
Disitamab vedotin (Synonyms: RC48) 纯度: 96.0%
Disitamab vedotin (RC48) 是一种抗体-药物偶联物 (ADC)，包含抗人表皮生长因子受体2 (HER2) 的单克隆抗体，该单克隆抗体通过可降解连接子结合到细胞毒性剂 MMAE。Disitamab vedotin 增强抗肿瘤免疫。
Disitamab vedotin Chemical Structure
CAS No. : 2136633-23-1
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 1 mg | ￥3400 | In-stock | |
| 5 mg | ￥10000 | In-stock | |
| 10 mg | 询价 | ||
| 50 mg | 询价 |
* Please select Quantity before adding items.
| 生物活性 |
Disitamab vedotin (RC48) is an antibody-drug conjugate (ADC) comprising a monoclonal antibody against human epidermal growth factor receptor 2 (HER2) conjugated via a cleavable linker to the cytotoxic agent Monomethyl auristatin E (MMAE). Disitamab vedotin enhances antitumor immunity[1]. |
|
|---|---|---|
| IC50 & Target[1] |
|
|
| 体外研究 (In Vitro) |
The antibody part was a humanized monoclonal antibody targeting HER2, the small molecule toxin was monomethyl auristatin E (MMAE), a synthetic antineoplastic agent. A protease cleavable linker covalently attached MMAE to the antibody[2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
|
| CAS 号 |
2136633-23-1 |
|
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
|
| 参考文献 |
|
所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务