GalNAc PEG DSPE Cat. No. PG2-DSGAN-5k 25 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

GalNAc PEG DSPE

Cat. No. PG2-DSGAN-5k
Specification
Unit Size 25 mg
Price $425.00

Qty Add to Cart

Synonym: N-Acetylgalactosamine PEG DSPE, GalNAc PEG DSPE, DSPE PEG GalNAc

Product Information:

  • Form: Solid/semi-solid;
  • Color: Colorless;
  • Lipid type: C18 saturated phospholipid;
  • PEG type: Linear PEG;
  • Ligand: GalNAc;

Storage Conditions:

  • Store at 4 0C or lower.

GlcNAc PEG DSPE Cat. No. PG2-DSGLN-5k 25 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

GlcNAc PEG DSPE

Cat. No. PG2-DSGLN-5k
Specification
Unit Size 25 mg
Price $485.00

Qty Add to Cart

Synonym: N-Acetylglucosamine PEG DSPE, GlcNAc PEG DSPE, DSPE PEG GlcNAc

Product Information:

  • Form: Solid/semi-solid;
  • Color: Colorless;
  • Lipid type: C18 saturated phospholipid;
  • PEG type: Linear PEG;
  • Ligand: GlcNAc (N-acetylglucosamine);

Storage Conditions:

  • Store at 4 0C or lower.

ManNAc PEG DSPE Cat. No. PG2-DSMAN-5k 20 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

ManNAc PEG DSPE

Cat. No. PG2-DSMAN-5k
Specification
Unit Size 20 mg
Price $485.00

Qty Add to Cart

Synonym: N-Acetylmannosamine PEG DSPE, ManNAc PEG DSPE, DSPE PEG ManNAc

Product Information:

  • Form: Solid/semi-solid;
  • Color: Colorless;
  • Lipid type: C18 saturated phospholipid;
  • PEG type: Linear PEG;
  • Ligand: ManNAc;

Storage Conditions:

  • Store at 4 0C or lower.

DSPE-NHS Cat. No. DS-NS-01 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE-NHS

Cat. No. DS-NS-01
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Synonym: NHS-DSPE, 1,2-distearoyl-sn-glycerol-phospho-ethanolamine-succinimidyl ester

Product Specification:

  • Appearance: Solid;
  • Color: white;
  • Lipid type: C18 saturated phospholipid;
  • Functional group: NHS ester;
  • Reactive to: Primary amine group;

Storage:

  • Store at -20 0C; 

Other Products:

DSPE-Maleimide, DSPE-Biotin, DSPE-PEG, DSPE-FITC, DSPE-Pyrene

DSPE Maleimide Cat. No. DS-ML-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE Maleimide

Cat. No. DS-ML-1
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Synonym: Maleimide-DSPE, 1,2-distearoyl-sn-glycerol-phospho-ethanolamine maleimide

Product Specification:

  • Appearance: Solid;
  • Color: white;
  • Lipid type: C18 saturated phospholipid;
  • Functional group: Maleimide;
  • Reactive to: Sulfhydryl group;

Storage:

  • Store at -20 0C; 

Other Products:

DSPE-NHS, DSPE-Biotin, DSPE-PEG, DSPE-FITC, DSPE-Pyrene

DSPE-Biotin Cat. No. DS-BN-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE-Biotin

Cat. No. DS-BN-1
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Synonym: Biotin-DSPE, 1,2-distearoyl-sn-glycerol-phospho-ethanolamine biotinylated

Product Specification:

  • Appearance: Solid;
  • Color: white;
  • Lipid type: C18 saturated phospholipid;
  • Functional group: Biton;
  • Reactive to: Avidin, streptavidin or neutravidin;

Storage:

  • Store at -20 0C; 

Other Products:

DSPE-Maleimide, DSPE-NHS, DSPE-PEG, DSPE-FITC, DSPE-Pyrene

DSPE-Pyrene Cat. No. DS-PR-01 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE-Pyrene

Cat. No. DS-PR-01
Specification
Unit Size 5 mg
Price $485.00

Qty Add to Cart

Synonym: Pyrene-DSPE, 1,2-distearoyl-sn-glycerol-phospho-ethanolamine pyrene

Product Specification:

  • Appearance: Solid;
  • Color: white;
  • Lipid type: C18 saturated phospholipid;
  • Functional group: Pyrene;
  • Ex/Em wavelength: 339nm/384 nm;

Storage:

  • Store at -20 0C; Protect from light.

Other Products:

DSPE-Maleimide, DSPE-Biotin, DSPE-PEG, DSPE-FITC, DSPE-Pyrene

DSPE Azide, Azido DSPE Cat. No. DS-AZ-1 25 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE Azide, Azido DSPE

Cat. No. DS-AZ-1
Specification
Unit Size 25 mg
Price $425.00

Qty Add to Cart

Synonym: Azide-DSPE, 1,2-distearoyl-sn-glycerol-phospho-ethanolamine azide, DSPE-N3

Product Specification:

  • Appearance: Solid;
  • Color: white;
  • Lipid type: C18 saturated phospholipid;
  • Functional group: Azide;
  • Reactive to: Alkyne;

Storage:

  • Store at -20 0C; 

Other Products:

DSPE-NHS, DSPE-Biotin, DSPE-PEG, DSPE-FITC, DSPE-Pyrene

DSPE DBCO Cat. No. DS-DB-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE DBCO

Cat. No. DS-DB-1
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Synonym: DBCO-DSPE, 1,2-distearoyl-sn-glycerol-phospho-ethanolamine DBCO

Product Specification:

  • Appearance: Solid;
  • Color: Pale yellow;
  • Lipid type: C18 saturated phospholipid;
  • Functional group: DBCO;
  • Reactive to: Azide/azido group;

Storage:

  • Store at -20 0C; 

Other Products:

DSPE-NHS, DSPE-Biotin, DSPE-PEG, DSPE-FITC, DSPE-Pyrene

DSPE Thiol Cat. No. DS-TH-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE Thiol

Cat. No. DS-TH-1
Specification
Unit Size 5 mg
Price $425.00

Qty Add to Cart

Synonym: Thiol-DSPE, 1,2-distearoyl-sn-glycerol-phospho-ethanolamine thiol

Product Specification:

  • Appearance: Solid;
  • Color: white;
  • Lipid type: C18 saturated phospholipid;
  • Functional group: Thiol;
  • Reactive to: Gold, Maleimide;

Storage:

  • Store at -20 0C; 

Other Products:

DSPE-NHS, DSPE-Biotin, DSPE-PEG, DSPE-FITC, DSPE-Pyrene

DSPE FITC Cat. No. DS-FC-1修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE FITC

Cat. No. DS-FC-1
Specification
Unit Size
Price $425.00

Qty Add to Cart

Synonym: FITC-DSPE, 1,2-distearoyl-sn-glycerol-phospho-ethanolamine fluorescein

Product Specification:

  • Appearance: Solid;
  • Color: Yellow/orange;
  • Lipid type: C18 saturated phospholipid;
  • Functional group: Fluorescein/FITC;
  • Ex/Em: 495 nm/515 nm;

Storage:

  • Store at -20 0C; Protect from light.

Other Products:

DSPE-NHS, DSPE-Biotin, DSPE-PEG, DSPE-FITC, DSPE-Pyrene

DSPE SPDP Cat. No. DS-PD-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE SPDP

Cat. No. DS-PD-1
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Synonym: SPDP-DSPE, 1,2-distearoyl-sn-glycerol-phospho-ethanolamine SPDP

Product Specification:

  • Appearance: Solid;
  • Color: white;
  • Lipid type: C18 saturated phospholipid;
  • Functional group: Pyridyl disulfide;
  • Reactive to: Sulfhydryl group;

Storage:

  • Store at -20 0C; 

Other Products:

DSPE-NHS, DSPE-Biotin, DSPE-PEG, DSPE-FITC, DSPE-Pyrene

DSPE-PEG46-N3

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

DSPE-PEG46-N3 

DSPE-PEG46-N3 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

DSPE-PEG46-N3

DSPE-PEG46-N3 Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

DSPE-PEG46-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

2843.51

Formula

C134H265N4O55P

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

DSPE-PEG46-N3

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

DSPE-PEG46-N3 

DSPE-PEG46-N3 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

DSPE-PEG46-N3

DSPE-PEG46-N3 Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

DSPE-PEG46-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

2843.51

Formula

C134H265N4O55P

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

DSPE-PEG36-mal

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

DSPE-PEG36-mal 

DSPE-PEG36-mal 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

DSPE-PEG36-mal

DSPE-PEG36-mal Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

DSPE-PEG36-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

2528.10

Formula

C121H232N3O48P

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

DSPE-PEG36-DBCO

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

DSPE-PEG36-DBCO 

DSPE-PEG36-DBCO 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

DSPE-PEG36-DBCO

DSPE-PEG36-DBCO Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

DSPE-PEG36-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

2664.29

Formula

C133H240N3O47P

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

DSPE-PEG46-DBCO

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

DSPE-PEG46-DBCO 

DSPE-PEG46-DBCO 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

DSPE-PEG46-DBCO

DSPE-PEG46-DBCO Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

DSPE-PEG46-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

3104.82

Formula

C153H280N3O57P

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

PEG2000-DSPE

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

PEG2000-DSPE  纯度: ≥95.0%

PEG2000-DSPE 可用于合成稳定的核酸脂质颗粒 (SNALPs)。SNALPs 代表了所描述的一些最早和功能最好的siRNA -ABC 纳米粒。

PEG2000-DSPE

PEG2000-DSPE Chemical Structure

规格 价格 是否有货 数量
5 mg ¥500 In-stock
10 mg ¥800 In-stock
25 mg ¥1600 In-stock
50 mg ¥2600 In-stock
100 mg ¥4100 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

PEG2000-DSPE 相关产品

相关化合物库:

  • Bioactive Compound Library Plus
  • Anti-Cancer Compound Library

生物活性

PEG2000-DSPE can be used for the preparation of stabilized nucleic acid-lipid particllipid particles (SNALPs). SNALPs represent some of the earliest and best functional siRNA-ABC nanoparticles described[1].

分子量

2808.74

Formula

C45H87NNaO11P

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro: 

DMSO : 12.5 mg/mL (4.45 mM; ultrasonic and warming and heat to 60°C)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.3560 mL 1.7802 mL 3.5603 mL
5 mM
10 mM

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 1.25 mg/mL (0.45 mM); Clear solution

    此方案可获得 ≥ 1.25 mg/mL (0.45 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 12.5 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂: 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 1.25 mg/mL (0.45 mM); Clear solution

    此方案可获得 ≥ 1.25 mg/mL (0.45 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 12.5 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
*以上所有助溶剂都可在 上海金畔生物科技有限公司 网站选购。
参考文献
  • [1]. Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013;10(6):781-811.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

DSPE PEG Maleimide, DSPE-PEG-MAL Cat. No. PG2-DSML-10k 10000 Da 100 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE PEG Maleimide, DSPE-PEG-MAL

Cat. No. PG2-DSML-10k DSPE PEG Maleimide, DSPE-PEG-MAL           Cat. No. PG2-DSML-10k     10000 Da    100 mg
Specification 10000 Da
Unit Size 100 mg
Price $385.00

Qty Add to Cart

Synonym: Maleimide PEG DSPE, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine PEG Maleimide, DSPE-PEG-Mal.

Description:

DSPE PEG Maleimide is one of Nanocs reactive phospholipid PEG  reagents that can react with sulfhydryl (thiol, -SH) groups. DSPE (1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine)  is a saturated 18C phospholipid that is highly hydrophobic. PEG linker (polyethylene glycol), on the other hand, offers good hydrophilicity and water solubility. Maleimide functional DSPE PEG has excellent reactivity towards sulfhydryl/thiol groups derived from various molecules. Reaction between maleimide and thiolproceeds easily at neutral pH. Maleimide PEG DSPE is one of most commonly used reactive phospholipids to conjugate antibodies, peptides or other ligands to the surface of liposome and other lipid PEG nanoparticles. Pegylated phospholipids have longer blood circulation time and higher stability for encapsulated drugs. Nanocs has developed a comprehensive collection of thiol reactive maleimide phospholipid PEG products that have high purity, various molecular weights and excellent chemical reactivity. These lipid PEG conjugates demonstrate excellent amphilphilic properties and offer superior advantages for small and large molecule drug formulation and delivery.

Physical Properties:

  • Form: Solid powder;
  • Color: White;
  • Solubility: Soluble in chloroform and warm water;
  • Reactive group: Maleimide;
  • Reactive to: Sulfhydryl (-SH);
  • Lipid type: 18C PE, saturated;
  • Purity: >95%

Storage Conditions:

  • Store at -20 0C. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Related Products
PG2-CADS-20k , DSPE PEG Acid, DSPE-PEG-COOH

DSPE PEG Maleimide, DSPE-PEG-MAL Cat. No. PG2-DSML-1k 1000 Da 100 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE PEG Maleimide, DSPE-PEG-MAL

Cat. No. PG2-DSML-1k DSPE PEG Maleimide, DSPE-PEG-MAL           Cat. No. PG2-DSML-1k     1000 Da    100 mg
Specification 1000 Da
Unit Size 100 mg
Price $425.00

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Synonym: Maleimide PEG DSPE, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine PEG Maleimide, DSPE-PEG-Mal.

Description:

DSPE PEG Maleimide is one of Nanocs reactive phospholipid PEG  reagents that can react with sulfhydryl (thiol, -SH) groups. DSPE (1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine)  is a saturated 18C phospholipid that is highly hydrophobic. PEG linker (polyethylene glycol), on the other hand, offers good hydrophilicity and water solubility. Maleimide functional DSPE PEG has excellent reactivity towards sulfhydryl/thiol groups derived from various molecules. Reaction between maleimide and thiolproceeds easily at neutral pH. Maleimide PEG DSPE is one of most commonly used reactive phospholipids to conjugate antibodies, peptides or other ligands to the surface of liposome and other lipid PEG nanoparticles. Pegylated phospholipids have longer blood circulation time and higher stability for encapsulated drugs. Nanocs has developed a comprehensive collection of thiol reactive maleimide phospholipid PEG products that have high purity, various molecular weights and excellent chemical reactivity. These lipid PEG conjugates demonstrate excellent amphilphilic properties and offer superior advantages for small and large molecule drug formulation and delivery.

Physical Properties:

  • Form: Solid powder;
  • Color: White;
  • Solubility: Soluble in chloroform and warm water;
  • Reactive group: Maleimide;
  • Reactive to: Sulfhydryl (-SH);
  • Lipid type: 18C PE, saturated;
  • Purity: >95%

Storage Conditions:

  • Store at -20 0C. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Related Products
PG2-CADS-1k , DSPE PEG Acid, DSPE-PEG-COOH