标签归档：epidioxyergosta

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol(Synonyms: 9,11-Dehydroergosterol peroxide; 9(11)-DHEP)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (Synonyms: 9,11-Dehydroergosterol peroxide; 9(11)-DHEP)

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide)，一种来自药用蘑菇的重要甾体，对几种肿瘤类型具有抗肿瘤活性。5,8-Epidioxyergosta-6,9(11),22-trien-3-ol 通过诱导 CDKN1A 表达抑制 HT29 细胞生长，从而导致细胞周期停滞和凋亡。

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol(Synonyms: 9,11-Dehydroergosterol peroxide; 9(11)-DHEP)

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol Chemical Structure

CAS No. : 86363-50-0

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide), an important steroid from medicinal mushroom, exerts antitumor activity in several tumor types. 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol inhibits HT29 cell growth by inducing CDKN1A expression, thus causing cell cycle arrest and apoptosis[1][2].

IC50 & Target[1]

Microbial Metabolite

 

体外研究
(In Vitro)

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide) is an effective inhibitor of HL60 leukemia cell growth and apoptosis-inducer[1].
Apoptosis induced by 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol from Ganoderma Lucidum mycelium in human malignant melanoma cells is Mcl‑1 dependent[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

426.63

Formula

C28H42O3
CAS 号

86363-50-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Kobori M, Yoshida M, Ohnishi-Kameyama M, Takei T, Shinmoto H. 5alpha,8alpha-Epidioxy-22E-ergosta-6,9(11),22-trien-3beta-ol from an edible mushroom suppresses growth of HL60 leukemia and HT29 colon adenocarcinoma cells. Biol Pharm Bull. 2006;29(4):755-759.

    [2]. Zheng L, et al. Apoptosis induced by 9,11 dehydroergosterol peroxide from Ganoderma Lucidum mycelium in human malignant melanoma cells is Mcl 1 dependent. Mol Med Rep. 2018;18(1):938-944.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol(Synonyms: 9,11-Dehydroergosterol peroxide; 9(11)-DHEP)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (Synonyms: 9,11-Dehydroergosterol peroxide; 9(11)-DHEP)

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide)，一种来自药用蘑菇的重要甾体，对几种肿瘤类型具有抗肿瘤活性。5,8-Epidioxyergosta-6,9(11),22-trien-3-ol 通过诱导 CDKN1A 表达抑制 HT29 细胞生长，从而导致细胞周期停滞和凋亡。

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol(Synonyms: 9,11-Dehydroergosterol peroxide; 9(11)-DHEP)

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol Chemical Structure

CAS No. : 86363-50-0

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide), an important steroid from medicinal mushroom, exerts antitumor activity in several tumor types. 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol inhibits HT29 cell growth by inducing CDKN1A expression, thus causing cell cycle arrest and apoptosis[1][2].

IC50 & Target[1]

Microbial Metabolite

 

体外研究
(In Vitro)

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide) is an effective inhibitor of HL60 leukemia cell growth and apoptosis-inducer[1].
Apoptosis induced by 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol from Ganoderma Lucidum mycelium in human malignant melanoma cells is Mcl‑1 dependent[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

426.63

Formula

C28H42O3
CAS 号

86363-50-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Kobori M, Yoshida M, Ohnishi-Kameyama M, Takei T, Shinmoto H. 5alpha,8alpha-Epidioxy-22E-ergosta-6,9(11),22-trien-3beta-ol from an edible mushroom suppresses growth of HL60 leukemia and HT29 colon adenocarcinoma cells. Biol Pharm Bull. 2006;29(4):755-759.

    [2]. Zheng L, et al. Apoptosis induced by 9,11 dehydroergosterol peroxide from Ganoderma Lucidum mycelium in human malignant melanoma cells is Mcl 1 dependent. Mol Med Rep. 2018;18(1):938-944.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol(Synonyms: 9,11-Dehydroergosterol peroxide; 9(11)-DHEP)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (Synonyms: 9,11-Dehydroergosterol peroxide; 9(11)-DHEP)

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide)，一种来自药用蘑菇的重要甾体，对几种肿瘤类型具有抗肿瘤活性。5,8-Epidioxyergosta-6,9(11),22-trien-3-ol 通过诱导 CDKN1A 表达抑制 HT29 细胞生长，从而导致细胞周期停滞和凋亡。

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol(Synonyms: 9,11-Dehydroergosterol peroxide; 9(11)-DHEP)

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol Chemical Structure

CAS No. : 86363-50-0

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide), an important steroid from medicinal mushroom, exerts antitumor activity in several tumor types. 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol inhibits HT29 cell growth by inducing CDKN1A expression, thus causing cell cycle arrest and apoptosis[1][2].

IC50 & Target[1]

Microbial Metabolite

 

体外研究
(In Vitro)

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide) is an effective inhibitor of HL60 leukemia cell growth and apoptosis-inducer[1].
Apoptosis induced by 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol from Ganoderma Lucidum mycelium in human malignant melanoma cells is Mcl‑1 dependent[2].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

426.63

Formula

C28H42O3
CAS 号

86363-50-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Kobori M, Yoshida M, Ohnishi-Kameyama M, Takei T, Shinmoto H. 5alpha,8alpha-Epidioxy-22E-ergosta-6,9(11),22-trien-3beta-ol from an edible mushroom suppresses growth of HL60 leukemia and HT29 colon adenocarcinoma cells. Biol Pharm Bull. 2006;29(4):755-759.

    [2]. Zheng L, et al. Apoptosis induced by 9,11 dehydroergosterol peroxide from Ganoderma Lucidum mycelium in human malignant melanoma cells is Mcl 1 dependent. Mol Med Rep. 2018;18(1):938-944.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务