标签归档：galnac

N-acetylgalactosamine PEG, GalNAc PEG Cat. No. PG1-GAN-5k 100 mg修饰性聚乙二醇

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N-acetylgalactosamine PEG, GalNAc PEG

Cat. No. PG1-GAN-5k
Specification
Unit Size 100 mg
Price $425.00

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Synonym: GalNAc PEG, N-acetylgalactosamine PEG, PEG GalNAc

Product information:

  • Form: Solid/semi-solid;
  • Color: White;
  • Solubility: Soluble in water or DMSO;

Storage Conditions:

  • Store at 4 0C or lower.

GalNAc PEG DSPE Cat. No. PG2-DSGAN-5k 25 mg修饰性聚乙二醇

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GalNAc PEG DSPE

Cat. No. PG2-DSGAN-5k
Specification
Unit Size 25 mg
Price $425.00

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Synonym: N-Acetylgalactosamine PEG DSPE, GalNAc PEG DSPE, DSPE PEG GalNAc

Product Information:

  • Form: Solid/semi-solid;
  • Color: Colorless;
  • Lipid type: C18 saturated phospholipid;
  • PEG type: Linear PEG;
  • Ligand: GalNAc;

Storage Conditions:

  • Store at 4 0C or lower.

GalNAc PEG Biotin Cat. No. PG2-BNGAN-5k 25 mg修饰性聚乙二醇

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GalNAc PEG Biotin

Cat. No. PG2-BNGAN-5k
Specification
Unit Size 25 mg
Price $425.00

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Synonym: N-acetylgalactosamine PEG Biotin, GalNAc PEG Biotin, Biotin PEG GalNAc.

Product information:

  • Form: Solid/semi-solid;
  • Color: Colorless;
  • Functional ligand: Biotin;
  • Targeting ligand: N-Acetylgalactosamine (GalNAc);
  • PEG type: Linear PEG

Storage:

  • Store at 4 0C or lower.

GalNAc PEG Azide Cat. No. PG2-AZGAN-5k 25 mg修饰性聚乙二醇

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GalNAc PEG Azide

Cat. No. PG2-AZGAN-5k
Specification
Unit Size 25 mg
Price $425.00

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Synonym: N-Acetylgalactosamine PEG Azide, GalNAc PEG Azide, Azide PEG GalNAc

Product Information:

  • Form: Solid/semi-solid;
  • Color: Colorless;
  • Reactive group: Azide;
  • PEG type: Linear PEG;
  • Ligand: GalNAc;

Storage Conditions:

  • Store at 4 0C or lower.

GalNAc-PEG-DBCO Cat. No. PG2-DBGAN-5k 25 mg修饰性聚乙二醇

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GalNAc-PEG-DBCO

Cat. No. PG2-DBGAN-5k
Specification
Unit Size 25 mg
Price $425.00

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Synonym: N-Acetylgalactosamine PEG DSPE, GalNAc PEG DBCO, DBCO PEG GalNAc

Product Information:

  • Form: Solid/semi-solid;
  • Color: Yellow;
  • Reactive group: DBCO;
  • PEG type: Linear PEG;
  • Ligand: GalNAc;

Storage Conditions:

  • Store at 4 0C or lower.

GalNAc PEG FITC Cat. No. PG2-FLGAN-5k 5 mg修饰性聚乙二醇

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GalNAc PEG FITC

Cat. No. PG2-FLGAN-5k
Specification
Unit Size 5 mg
Price $485.00

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Synonym: N-Acetylgalactosamine PEG FITC, GalNAc PEG FITC, FITCE PEG GalNAc

Product Information:

  • Form: Solid/semi-solid;
  • Color: Yellow/orange;
  • Fluorophore: Fluorescein, ex/em 495/515 nm;
  • PEG type: Linear PEG;
  • Ligand: GalNAc;

Storage Conditions:

  • Store at 4 0C or lower. Protect from light.

GalNAc PEG Cholesterol Cat. No. PG2-CSGAN-5k 25 mg修饰性聚乙二醇

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GalNAc PEG Cholesterol

Cat. No. PG2-CSGAN-5k
Specification
Unit Size 25 mg
Price $425.00

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Synonym: N-Acetylgalactosamine PEG Cholesterol, GalNAc PEG Cholesterol, Cholesterol PEG GalNAc

Product Information:

  • Form: Solid/semi-solid;
  • Color: Colorless;
  • Lipid type: Cholesterol;
  • PEG type: Linear PEG;
  • Ligand: GalNAc;

Storage Conditions:

  • Store at 4 0C or lower.

Agarose beads, GalNAc Conjugate Cat. No. AR-GAN-1 4B 5 mL修饰性聚乙二醇

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Agarose beads, GalNAc Conjugate

Cat. No. AR-GAN-1
Specification 4B
Unit Size 5 mL
Price $485.00

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Synonym: N-Acetylgalactosamine agarose conjugate, GalNAc conjugated agarose

Product information:

  • Bead type: 4% crosslinked agarose beads;
  • Bead size: 50-150 um;
  • Ligand: GalNAc (N-acetylgalactosamine);
  • Loading density: 5-20 mg GalNAc per mL settled beads;
  • Bead solution: 20% alcohol in water.

Storage conditions:

  • Store at 4 0C.  

Benzyl-α-GalNAc

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Benzyl-α-GalNAc  纯度: 98.23%

Benzyl-α-GalNAc 是一种有效的 O-糖基化 (O-glycosylation) 抑制剂，用于减少细胞表面的粘蛋白。Benzyl-α-GalNAc 抑制人胰腺癌细胞模型黏蛋白 O-糖基化的合成。

Benzyl-α-GalNAc

Benzyl-α-GalNAc Chemical Structure

CAS No. : 3554-93-6

规格 价格 是否有货 数量
10 mM * 1 mL in Water ￥2200 In-stock
25 mg ￥2000 询价
100 mg ￥5500 询价
200 mg   询价  
500 mg   询价  

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Benzyl-α-GalNAc 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • Anti-Cancer Compound Library
  • Anti-Pancreatic Cancer Compound Library

生物活性

Benzyl-α-GalNAc is a potent O-glycosylation inhibitor and is used to reduce mucin on cell surfaces. Benzyl-α-GalNAc inhibits the synthesis of mucin O-glycosylation of cellular models of human pancreatic cancer[1].

IC50 & Target

O-glycosylation[1]
分子量

311.33

Formula

C15H21NO6
CAS 号

3554-93-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

H2O : 8.33 mg/mL (26.76 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.2120 mL 16.0601 mL 32.1203 mL
5 mM 0.6424 mL 3.2120 mL 6.4241 mL
10 mM 0.3212 mL 1.6060 mL 3.2120 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Kalra AV, et al. Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: overcoming cellular barriers for therapeutic gain. Br J Cancer. 2007 Oct 8;97(7):910-8. Epub 2007 Oct 2.

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tri-GalNAc-COOH

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

tri-GalNAc-COOH 

tri-GalNAc-COOH 是一种去唾液酸糖蛋白受体 (ASGPR) 配体，可用于溶酶体靶向嵌合体 (LYTAC) 研究。

tri-GalNAc-COOH

tri-GalNAc-COOH Chemical Structure

CAS No. : 1953146-81-0

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research[1].

体外研究
(In Vitro)

tri-GalNAc-COOH is a biotin-free ASGPR ligand, which failes to deliver NA-650 to HepG2, Huh7, or A549 cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1735.91

Formula

C75H134N10O35
CAS 号

1953146-81-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Yaxian Zhou, et al. Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins. ACS Cent Sci. 2021 Mar 24;7(3):499-506.

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多肽定制[alpha-GalNAc-Ser]-Erythropoietin (Epo)) 编码

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名称 [alpha-GalNAc-Ser]-Erythropoietin (Epo))
编码
别名 [alpha-GalNAc-Ser]-Erythropoietin (Epo))
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） EAISPPDAA-*S-AAPLR (*S=GalNAc-Ser)
序列（三字母缩写） H-Glu-Ala-Ile-Ser-Pro-Pro-Asp-Ala-Ala-*Ser-Ala-Ala-Pro-Leu-Arg-OH (*Ser=GalNAc-Ser) (trifluoroacetate salt)
基本描述
溶解度
分子量 1668.6
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents [alpha-GalNAc-Ser]-Erythropoietin (Epo)) 编码
Figures [alpha-GalNAc-Ser]-Erythropoietin (Epo)) 编码
Reference Nimtz, et al. Eur. J. Biochem. 213, 39 (1993)
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