标签归档：geranoxy

5-Geranoxy-7-methoxycoumarin

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

5-Geranoxy-7-methoxycoumarin 

5-Geranoxy-7-methoxycoumarin 是一种具有抗癌、抗真菌和抗菌活性的香豆素。5-Geranoxy-7-methoxycoumarin 诱导细胞凋亡(apoptosis)。

5-Geranoxy-7-methoxycoumarin

5-Geranoxy-7-methoxycoumarin Chemical Structure

CAS No. : 7380-39-4

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

5-Geranoxy-7-methoxycoumarin is a coumarin with anti-cancer, antifungal, and  antibacterial activities. 5-Geranoxy-7-methoxycoumarin induces cell apoptosis[1][2].

体外研究
(In Vitro)

5-Geranoxy-7-methoxycoumarin (12.5-200 µM; 24-72 hours) induces a significant inhibition of cell growth in a time-dependent manner in SW480 cells[1].
5-Geranoxy-7-methoxycoumarin (50 µM;48 hours) promotes DNA fragmentation and causes apoptosis through inhibition of the p38 MAPK signaling pathway in SW480 cells[1].
5-Geranoxy-7-methoxycoumarin (50 µM; 24-48 hours) increases the percentage of cells in the sub G1/G0 phase from 5.3% (in control cells) to 18% after 48 h incubation[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: SW480
Concentration: 0-20 μM
Incubation Time: 24, 48 and 72 hours
Result: Inhibited cell growth by 67% at 72 hours.

Apoptosis Analysis[1]

Cell Line: SW480 cells
Concentration: 50 μM
Incubation Time: 48 hours
Result: Induced cell apoptosis.

Cell Cycle Analysis[1]

Cell Line: SW480 cells
Concentration: 50 μM
Incubation Time: 48 hours
Result: Inhibited cell cycle progression in vitro.

分子量

328.40

Formula

C20H24O4
CAS 号

7380-39-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Jaiprakash R Patil, et al. 5-Geranyloxy-7-methoxycoumarin inhibits colon cancer (SW480) cells growth by inducing apoptosis. Planta Med. 2013 Mar;79(3-4):219-26.

    [2]. Guo-Ying Zuo, et al. Synergism of coumarins from the Chinese drug Zanthoxylum nitidum with antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA). Phytomedicine

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

5-Geranoxy-7-methoxycoumarin

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

5-Geranoxy-7-methoxycoumarin 

5-Geranoxy-7-methoxycoumarin 是一种具有抗癌、抗真菌和抗菌活性的香豆素。5-Geranoxy-7-methoxycoumarin 诱导细胞凋亡(apoptosis)。

5-Geranoxy-7-methoxycoumarin

5-Geranoxy-7-methoxycoumarin Chemical Structure

CAS No. : 7380-39-4

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

5-Geranoxy-7-methoxycoumarin is a coumarin with anti-cancer, antifungal, and  antibacterial activities. 5-Geranoxy-7-methoxycoumarin induces cell apoptosis[1][2].

体外研究
(In Vitro)

5-Geranoxy-7-methoxycoumarin (12.5-200 µM; 24-72 hours) induces a significant inhibition of cell growth in a time-dependent manner in SW480 cells[1].
5-Geranoxy-7-methoxycoumarin (50 µM;48 hours) promotes DNA fragmentation and causes apoptosis through inhibition of the p38 MAPK signaling pathway in SW480 cells[1].
5-Geranoxy-7-methoxycoumarin (50 µM; 24-48 hours) increases the percentage of cells in the sub G1/G0 phase from 5.3% (in control cells) to 18% after 48 h incubation[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: SW480
Concentration: 0-20 μM
Incubation Time: 24, 48 and 72 hours
Result: Inhibited cell growth by 67% at 72 hours.

Apoptosis Analysis[1]

Cell Line: SW480 cells
Concentration: 50 μM
Incubation Time: 48 hours
Result: Induced cell apoptosis.

Cell Cycle Analysis[1]

Cell Line: SW480 cells
Concentration: 50 μM
Incubation Time: 48 hours
Result: Inhibited cell cycle progression in vitro.

分子量

328.40

Formula

C20H24O4
CAS 号

7380-39-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Jaiprakash R Patil, et al. 5-Geranyloxy-7-methoxycoumarin inhibits colon cancer (SW480) cells growth by inducing apoptosis. Planta Med. 2013 Mar;79(3-4):219-26.

    [2]. Guo-Ying Zuo, et al. Synergism of coumarins from the Chinese drug Zanthoxylum nitidum with antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA). Phytomedicine

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

5-Geranoxy-7-methoxycoumarin

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

5-Geranoxy-7-methoxycoumarin 

5-Geranoxy-7-methoxycoumarin 是一种具有抗癌、抗真菌和抗菌活性的香豆素。5-Geranoxy-7-methoxycoumarin 诱导细胞凋亡(apoptosis)。

5-Geranoxy-7-methoxycoumarin

5-Geranoxy-7-methoxycoumarin Chemical Structure

CAS No. : 7380-39-4

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

5-Geranoxy-7-methoxycoumarin is a coumarin with anti-cancer, antifungal, and  antibacterial activities. 5-Geranoxy-7-methoxycoumarin induces cell apoptosis[1][2].

体外研究
(In Vitro)

5-Geranoxy-7-methoxycoumarin (12.5-200 µM; 24-72 hours) induces a significant inhibition of cell growth in a time-dependent manner in SW480 cells[1].
5-Geranoxy-7-methoxycoumarin (50 µM;48 hours) promotes DNA fragmentation and causes apoptosis through inhibition of the p38 MAPK signaling pathway in SW480 cells[1].
5-Geranoxy-7-methoxycoumarin (50 µM; 24-48 hours) increases the percentage of cells in the sub G1/G0 phase from 5.3% (in control cells) to 18% after 48 h incubation[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: SW480
Concentration: 0-20 μM
Incubation Time: 24, 48 and 72 hours
Result: Inhibited cell growth by 67% at 72 hours.

Apoptosis Analysis[1]

Cell Line: SW480 cells
Concentration: 50 μM
Incubation Time: 48 hours
Result: Induced cell apoptosis.

Cell Cycle Analysis[1]

Cell Line: SW480 cells
Concentration: 50 μM
Incubation Time: 48 hours
Result: Inhibited cell cycle progression in vitro.

分子量

328.40

Formula

C20H24O4
CAS 号

7380-39-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Jaiprakash R Patil, et al. 5-Geranyloxy-7-methoxycoumarin inhibits colon cancer (SW480) cells growth by inducing apoptosis. Planta Med. 2013 Mar;79(3-4):219-26.

    [2]. Guo-Ying Zuo, et al. Synergism of coumarins from the Chinese drug Zanthoxylum nitidum with antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA). Phytomedicine

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务