PNU-EDA-Gly5

发表于2024年12月20日由上海金畔生物科技有限公司

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

PNU-EDA-Gly5

PNU-EDA-Gly5 是用于ADC 合成的低聚甘氨酸毒素分子偶联物，由 DNA 拓扑异构酶 I 抑制剂 PNU-159682 和 EDA-Gly5 里连接子组成。

PNU-EDA-Gly5 Chemical Structure

CAS No. : 1957223-28-7

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	PNU-EDA-Gly5 is an oligo-glycine linker-payload for ADC synthesis, composed of a DNA topoisomerase I inhibitor PNU-159682 and a linker EDA-Gly5^[1].
分子量	954.93
Formula	C₄₃H₅₄N₈O₁₇
CAS 号	1957223-28-7
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Quintieri L, et al. Formation and antitumor activity of PNU-159682, a major metabolite of nemorubicin in human liver microsomes. Clin Cancer Res. 2005 Feb 15;11(4):1608-17.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

PNU-EDA-Gly5

发表于2024年12月20日由上海金畔生物科技有限公司

PNU-EDA-Gly5

PNU-EDA-Gly5 是用于ADC 合成的低聚甘氨酸毒素分子偶联物，由 DNA 拓扑异构酶 I 抑制剂 PNU-159682 和 EDA-Gly5 里连接子组成。

PNU-EDA-Gly5 Chemical Structure

CAS No. : 1957223-28-7

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	PNU-EDA-Gly5 is an oligo-glycine linker-payload for ADC synthesis, composed of a DNA topoisomerase I inhibitor PNU-159682 and a linker EDA-Gly5^[1].
分子量	954.93
Formula	C₄₃H₅₄N₈O₁₇
CAS 号	1957223-28-7
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Quintieri L, et al. Formation and antitumor activity of PNU-159682, a major metabolite of nemorubicin in human liver microsomes. Clin Cancer Res. 2005 Feb 15;11(4):1608-17.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

PNU-EDA-Gly5

发表于2024年12月20日由上海金畔生物科技有限公司

PNU-EDA-Gly5

PNU-EDA-Gly5 是用于ADC 合成的低聚甘氨酸毒素分子偶联物，由 DNA 拓扑异构酶 I 抑制剂 PNU-159682 和 EDA-Gly5 里连接子组成。

PNU-EDA-Gly5 Chemical Structure

CAS No. : 1957223-28-7

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	PNU-EDA-Gly5 is an oligo-glycine linker-payload for ADC synthesis, composed of a DNA topoisomerase I inhibitor PNU-159682 and a linker EDA-Gly5^[1].
分子量	954.93
Formula	C₄₃H₅₄N₈O₁₇
CAS 号	1957223-28-7
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Quintieri L, et al. Formation and antitumor activity of PNU-159682, a major metabolite of nemorubicin in human liver microsomes. Clin Cancer Res. 2005 Feb 15;11(4):1608-17.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

多肽定制Substance P-Gly-Lys-Arg 编码

发表于2024年11月17日由上海金畔生物科技有限公司

上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称	Substance P-Gly-Lys-Arg
编码
别名	Substance P-Gly-Lys-Arg
纯度	80%，90%，95%，98%，99%
重量	1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写）	RPKPQQFFGLMGKR
序列（三字母缩写）	Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-Gly-Lys-Arg
基本描述
溶解度
分子量	1690.06
化学式	C77H124N24O17S
存储条件	Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents
Figures
Reference
C端
N端
化学桥

Suc-Gly-Pro-AMC

发表于2024年11月12日由上海金畔生物科技有限公司

Suc-Gly-Pro-AMC

Suc-Gly-Pro-AMC 是一种成纤维细胞活化蛋白 (FAP) 特异性底物。Suc-Gly-Pro-AMC 可用于研究 FAP 的活性。

Suc-Gly-Pro-AMC Chemical Structure

CAS No. : 80049-85-0

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	Suc-Gly-Pro-AMC is a fibroblast activation protein (FAP)-specific substrate. Suc-Gly-Pro-AMC can be used to study the activity of FAP^[1].
分子量	429.42
Formula	C₂₁H₂₃N₃O₇
CAS 号	80049-85-0
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Zhang B, et, al. A cell-based fluorescent assay for FAP inhibitor discovery. Bioorg Med Chem Lett. 2020 Jul 15;30(14):127253.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Suc-Gly-Pro-AMC

发表于2024年11月12日由上海金畔生物科技有限公司

Suc-Gly-Pro-AMC

Suc-Gly-Pro-AMC 是一种成纤维细胞活化蛋白 (FAP) 特异性底物。Suc-Gly-Pro-AMC 可用于研究 FAP 的活性。

Suc-Gly-Pro-AMC Chemical Structure

CAS No. : 80049-85-0

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	Suc-Gly-Pro-AMC is a fibroblast activation protein (FAP)-specific substrate. Suc-Gly-Pro-AMC can be used to study the activity of FAP^[1].
分子量	429.42
Formula	C₂₁H₂₃N₃O₇
CAS 号	80049-85-0
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Zhang B, et, al. A cell-based fluorescent assay for FAP inhibitor discovery. Bioorg Med Chem Lett. 2020 Jul 15;30(14):127253.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Suc-Gly-Pro-AMC

发表于2024年11月12日由上海金畔生物科技有限公司

Suc-Gly-Pro-AMC

Suc-Gly-Pro-AMC 是一种成纤维细胞活化蛋白 (FAP) 特异性底物。Suc-Gly-Pro-AMC 可用于研究 FAP 的活性。

Suc-Gly-Pro-AMC Chemical Structure

CAS No. : 80049-85-0

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	Suc-Gly-Pro-AMC is a fibroblast activation protein (FAP)-specific substrate. Suc-Gly-Pro-AMC can be used to study the activity of FAP^[1].
分子量	429.42
Formula	C₂₁H₂₃N₃O₇
CAS 号	80049-85-0
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Zhang B, et, al. A cell-based fluorescent assay for FAP inhibitor discovery. Bioorg Med Chem Lett. 2020 Jul 15;30(14):127253.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

多肽定制TRH-Gly 编码 [85344-77-0]

发表于2024年11月10日由上海金畔生物科技有限公司

上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称	TRH-Gly
编码	[85344-77-0]
别名	TRH-Gly
纯度	80%，90%，95%，98%，99%
重量	1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写）	Pyr-HPG-OH
序列（三字母缩写）	Pyr-His-Pro-Gly
基本描述
溶解度
分子量	0
化学式
存储条件	Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents
Figures
Reference
C端
N端
化学桥

多肽定制Trp-Gly 编码 [7360-09-0]

发表于2024年11月10日由上海金畔生物科技有限公司

上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称	Trp-Gly
编码	[7360-09-0]
别名	Trp-Gly
纯度	80%，90%，95%，98%，99%
重量	1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写）	WG
序列（三字母缩写）	Trp-Gly
基本描述
溶解度
分子量	261.2
化学式	C13H15N3O3
存储条件	Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents
Figures
Reference
C端
N端
化学桥

多肽定制Tyr-Lys-Gly-(Cyclo(Glu26-Lys29),Pro34)-Neuropeptide Y (25-36) 编码 [185032-24-0]

发表于2024年11月8日由上海金畔生物科技有限公司

上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称	Tyr-Lys-Gly-(Cyclo(Glu26-Lys29),Pro34)-Neuropeptide Y (25-36)
编码	[185032-24-0]
别名	Tyr-Lys-Gly-(Cyclo(Glu26-Lys29),Pro34)-Neuropeptide Y (25-36)
纯度	80%，90%，95%，98%，99%
重量	1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写）	YKGR-cyclo(-EYI-Lys)-LI TRPRY-NH2
序列（三字母缩写）	Tyr-Lys-Gly-Arg-cyclo(-Glu-Tyr-Ile-Lys)-Leu-Ile-Thr-Arg-Pro-Arg-Tyr-NH2
基本描述
溶解度
分子量	0
化学式
存储条件	Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents
Figures
Reference
C端
N端
化学桥

N’-Boc-N-(Gly-Oleoyl)-Lys

发表于2024年11月8日由上海金畔生物科技有限公司

N’-Boc-N-(Gly-Oleoyl)-Lys

N’-Boc-N-(Gly-Oleoyl)-Lys 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。

N’-Boc-N-(Gly-Oleoyl)-Lys Chemical Structure

CAS No. : 2353409-71-7

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

N’-Boc-N-(Gly-Oleoyl)-Lys is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

Alkyl-Chain

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

567.80

Formula

C₃₁H₅₇N₃O₆

CAS 号

2353409-71-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

N’-Boc-N-(Gly-Oleoyl)-Lys

发表于2024年11月8日由上海金畔生物科技有限公司

N’-Boc-N-(Gly-Oleoyl)-Lys

N’-Boc-N-(Gly-Oleoyl)-Lys 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。

N’-Boc-N-(Gly-Oleoyl)-Lys Chemical Structure

CAS No. : 2353409-71-7

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

N’-Boc-N-(Gly-Oleoyl)-Lys is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

Alkyl-Chain

体外研究
(In Vitro)

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

567.80

Formula

C₃₁H₅₇N₃O₆

CAS 号

2353409-71-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

N’-Boc-N-(Gly-Oleoyl)-Lys

发表于2024年11月8日由上海金畔生物科技有限公司

N’-Boc-N-(Gly-Oleoyl)-Lys

N’-Boc-N-(Gly-Oleoyl)-Lys 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。

N’-Boc-N-(Gly-Oleoyl)-Lys Chemical Structure

CAS No. : 2353409-71-7

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

N’-Boc-N-(Gly-Oleoyl)-Lys is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

Alkyl-Chain

体外研究
(In Vitro)

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

567.80

Formula

C₃₁H₅₇N₃O₆

CAS 号

2353409-71-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

多肽定制Z-Gly-Pro-Arg-AMC · HCl 编码 [201928-42-9]

发表于2024年10月31日由上海金畔生物科技有限公司

上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称	Z-Gly-Pro-Arg-AMC · HCl
编码	[201928-42-9]
别名	Z-Gly-Pro-Arg-AMC · HCl
纯度	80%，90%，95%，98%，99%
重量	1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写）	ZGPR-AMC
序列（三字母缩写）	Z-Gly-Pro-Arg-AMC (hydrochloride salt)
基本描述
溶解度
分子量	619.7
化学式	C31H37N7O7
存储条件	Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents
Figures
Reference
C端
N端
化学桥

Arg-Gly-Glu-Ser

发表于2024年10月28日由上海金畔生物科技有限公司

Arg-Gly-Glu-Ser

Arg-Gly-Glu-Ser 是一种与 RGD 有关的多肽，控制 RGDS 对纤维蛋白原与激活的血小板结合的抑制活动。

Arg-Gly-Glu-Ser Chemical Structure

CAS No. : 93674-97-6

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

Arg-Gly-Glu-Ser 的其他形式现货产品:

Arg-Gly-Glu-Ser TFA

生物活性

Arg-Gly-Glu-Ser is a RGD-related peptide and a control for the RGDS ihibitory activity on fibrinogen binding to activated platelets.

体内研究
(In Vivo)

Arg-Gly-Glu-Ser (5 mg/kg) in combination with LPS or saline + RGDS does not affect neutrophil and macrophage cell numbers and has no effect on protein accumulation compared with LPS- or saline-treated mice, respectively^[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

447.44

Formula

C₁₆H₂₉N₇O₈

CAS 号

93674-97-6

Sequence

Arg-Gly-Glu-Ser

Sequence Shortening

RGES

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

溶解性数据

In Vitro:

H₂O : 2 mg/mL (4.47 mM; Need ultrasonic and warming)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.2349 mL	11.1747 mL	22.3494 mL
5 mM	—	—	—
10 mM	—	—	—

参考文献

[1]. Moon C, et al. Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways. Respir Res. 2009 Mar 9;10:18.

Animal Administration ^[1]	Mice^[1] Mouse pharyngeal aspiration is performed in the assay. Animals are anesthetized with a mixture of ketamine and xylazine (45 mg/kg and 8 mg/kg, i.p., respectively). Test solution (30 μL) containing LPS (1.5 mg/kg) is placed posterior in the throat and aspirated into the lungs. Control mice are administrated sterile saline (0.9% NaCl). Animals are administered with RGDS or Arg-Gly-Glu-Ser peptide (1, 2.5 or 5 mg/kg, i.p.) once one hour before LPS treatment and sacrificed 4 h post-LPS. Animals are also administered RGDS or Arg-Gly-Glu-Ser peptide (5 mg/kg, i.p.) once at different time points (1 h before or 2 h after LPS treatment) and sacrificed 24 h post-LPS. In addition, animals are administered with αvβ3-blocking mAbs, anti-αv, or anti-β3 (5 mg/kg, i.p.) once 1 h before and sacrificed 4 h post-LPS. Animals administered with these mAbs 2 h after LPS treatment are sacrificed 24 h post-LPS^[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献	[1]. Moon C, et al. Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways. Respir Res. 2009 Mar 9;10:18.

Animal Administration
^[1]

Mice^[1]
Mouse pharyngeal aspiration is performed in the assay. Animals are anesthetized with a mixture of ketamine and xylazine (45 mg/kg and 8 mg/kg, i.p., respectively). Test solution (30 μL) containing LPS (1.5 mg/kg) is placed posterior in the throat and aspirated into the lungs. Control mice are administrated sterile saline (0.9% NaCl). Animals are administered with RGDS or Arg-Gly-Glu-Ser peptide (1, 2.5 or 5 mg/kg, i.p.) once one hour before LPS treatment and sacrificed 4 h post-LPS. Animals are also administered RGDS or Arg-Gly-Glu-Ser peptide (5 mg/kg, i.p.) once at different time points (1 h before or 2 h after LPS treatment) and sacrificed 24 h post-LPS. In addition, animals are administered with αvβ3-blocking mAbs, anti-αv, or anti-β3 (5 mg/kg, i.p.) once 1 h before and sacrificed 4 h post-LPS. Animals administered with these mAbs 2 h after LPS treatment are sacrificed 24 h post-LPS^[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献

[1]. Moon C, et al. Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways. Respir Res. 2009 Mar 9;10:18.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Tyr-Gly-Gly-Phe-Met-OH(Synonyms: 蛋氨酸脑啡肽; Met-Enkephalin; Methionine enkephalin)

发表于2024年10月21日由上海金畔生物科技有限公司

Tyr-Gly-Gly-Phe-Met-OH (Synonyms: 蛋氨酸脑啡肽; Met-Enkephalin; Methionine enkephalin) 纯度: 98.07%

Tyr-Gly-Gly-Phe-Met-OH 通过结合阿片样物质受体 (opioid receptor)，可调控人类免疫功能，抑制肿瘤生长。

Tyr-Gly-Gly-Phe-Met-OH Chemical Structure

CAS No. : 58569-55-4

规格	价格	是否有货
Free Sample (0.1-0.5 mg)		Apply now
10 mM * 1 mL in Water	￥550	In-stock
10 mg	￥500	In-stock
25 mg	￥950	In-stock
50 mg	￥1600	In-stock
100 mg	￥2600	In-stock
200 mg		询价
500 mg		询价

* Please select Quantity before adding items.

Tyr-Gly-Gly-Phe-Met-OH 相关产品

•相关化合物库:

Bioactive Compound Library Plus
GPCR/G Protein Compound Library
Neuronal Signaling Compound Library
Anti-Cancer Compound Library
Peptidomimetic Library
Neurotransmitter Receptor Compound Library
Rare Diseases Drug Library
Peptide Library

生物活性

Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.

IC₅₀ & Target

Opioid Receptor^[1].

体外研究
(In Vitro)

Methionine enkephalin (MENK), an endogenous neuropeptide has a crucial role in both neuroendocrine and immune systems. MENK is believed to have an immunoregulatory activity to have cancer biotherapy activity by binding to the opioid receptors on immune and cancer cells. MENK may also change the tumor microenvironment by binding to opioid receptor on or in cancer cells. All of these mechanisms of action have biologic significance and potential for use in cancer immunotherapy. Furthermore, they reveal a relationship between the endocrine and immune systems^[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

573.66

Formula

C₂₇H₃₅N₅O₇S

CAS 号

58569-55-4

Sequence

Tyr-Gly-Gly-Phe-Met

Sequence Shortening

YGGFM

中文名称

蛋氨酸脑啡肽

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-80°C	2 years
	-20°C	1 year
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : ≥ 40 mg/mL (69.73 mM)

H₂O : 6.67 mg/mL (11.63 mM; Need ultrasonic)

* “≥” means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.7432 mL	8.7160 mL	17.4319 mL
5 mM	0.3486 mL	1.7432 mL	3.4864 mL
10 mM	0.1743 mL	0.8716 mL	1.7432 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

参考文献

[1]. Zhao D, et al. Methionine enkephalin, its role in immunoregulation and cancer therapy. Int Immunopharmacol. 2016 Feb 23. pii: S1567-5769(16)30050-9.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

MC-Gly-Gly-Phe

发表于2024年10月19日由上海金畔生物科技有限公司

MC-Gly-Gly-Phe 纯度: 96.57%

MC-Gly-Gly-Phe 是一种可降解 (cleavable) 的 linker，可用于抗体偶联药物 (ADC)。

MC-Gly-Gly-Phe Chemical Structure

CAS No. : 1599440-15-9

规格	价格	是否有货
10 mg	￥2950	In-stock
50 mg	￥8800	In-stock
100 mg	￥14000	In-stock
200 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).

IC₅₀ & Target

Cleavable

分子量

472.49

Formula

C₂₃H₂₈N₄O₇

CAS 号

1599440-15-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : 50 mg/mL (105.82 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.1164 mL	10.5822 mL	21.1645 mL
5 mM	0.4233 mL	2.1164 mL	4.2329 mL
10 mM	0.2116 mL	1.0582 mL	2.1164 mL

参考文献

[1]. Antibody-drug conjugate. WO2014057687A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Fmoc-Gly-Gly-D-Phe-OH

发表于2024年10月7日由上海金畔生物科技有限公司

Fmoc-Gly-Gly-D-Phe-OH

Fmoc-Gly-Gly-D-Phe-OH 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体药物结合物 (ADCs) 的合成。Fmoc-Gly-Gly-D-Phe-OH 是 Fmoc-Gly-Gly-Phe-OH (HY-131833) 的 D 型异构体。

Fmoc-Gly-Gly-D-Phe-OH Chemical Structure

规格	价格	是否有货
250 mg	￥6500	询问价格 & 货期

* Please select Quantity before adding items.

生物活性

Fmoc-Gly-Gly-D-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OH is the D-isomer of Fmoc-Gly-Gly-Phe-OH (HY-131833).

IC₅₀ & Target

Cleavable

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

501.53

Formula

C₂₈H₂₇N₃O₆

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Mc-Gly-Gly-Phe-Gly-PAB-OH TFA(Synonyms: Mc-GGFG-PAB-OH TFA)

发表于2024年9月27日由上海金畔生物科技有限公司

Mc-Gly-Gly-Phe-Gly-PAB-OH TFA (Synonyms: Mc-GGFG-PAB-OH TFA) 纯度: 96.81%

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA 是一种可降解 (cleavable) 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

Mc-Gly-Gly-Phe-Gly-PAB-OH TFA Chemical Structure

规格	价格	是否有货
25 mg	￥3300	In-stock
50 mg	￥5300	In-stock
100 mg	￥8500	In-stock
200 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

IC₅₀ & Target^[1]

Cleavable

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

748.70

Formula

C₃₄H₃₉F₃N₆O₁₀

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据

In Vitro:

DMSO : 250 mg/mL (333.91 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.3356 mL	6.6782 mL	13.3565 mL
5 mM	0.2671 mL	1.3356 mL	2.6713 mL
10 mM	0.1336 mL	0.6678 mL	1.3356 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline

Solubility: ≥ 2.08 mg/mL (2.78 mM); Clear solution

此方案可获得 ≥ 2.08 mg/mL (2.78 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液
2.

请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (2.78 mM); Clear solution

此方案可获得 ≥ 2.08 mg/mL (2.78 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明

*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

多肽定制(Sar1,Gly8)-Angiotensin II 编码 [51887-62-8]

发表于2024年9月4日由上海金畔生物科技有限公司

上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称	(Sar1,Gly8)-Angiotensin II
编码	[51887-62-8]
别名	(Sar1,Gly8)-Angiotensin II
纯度	80%，90%，95%，98%，99%
重量	1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写）	Sar-RVYIHPG-OH
序列（三字母缩写）	Sar-Arg-Val-Tyr-Ile-His-Pro-Gly
基本描述
溶解度
分子量	0
化学式
存储条件	Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents
Figures
Reference
C端
N端
化学桥

whatman (沃特曼)

英国沃特曼 Millipore PALL中国代理商金畔官网

标签归档：gly

PNU-EDA-Gly5

PNU-EDA-Gly5

PNU-EDA-Gly5

多肽定制Substance P-Gly-Lys-Arg 编码

Suc-Gly-Pro-AMC

Suc-Gly-Pro-AMC

Suc-Gly-Pro-AMC

多肽定制TRH-Gly 编码 [85344-77-0]

多肽定制Trp-Gly 编码 [7360-09-0]

多肽定制Tyr-Lys-Gly-(Cyclo(Glu26-Lys29),Pro34)-Neuropeptide Y (25-36) 编码 [185032-24-0]

N’-Boc-N-(Gly-Oleoyl)-Lys

N’-Boc-N-(Gly-Oleoyl)-Lys

N’-Boc-N-(Gly-Oleoyl)-Lys

多肽定制Z-Gly-Pro-Arg-AMC · HCl 编码 [201928-42-9]

Arg-Gly-Glu-Ser

Tyr-Gly-Gly-Phe-Met-OH(Synonyms: 蛋氨酸脑啡肽; Met-Enkephalin; Methionine enkephalin)

Tyr-Gly-Gly-Phe-Met-OH 相关产品

•相关化合物库:

MC-Gly-Gly-Phe

Fmoc-Gly-Gly-D-Phe-OH

Mc-Gly-Gly-Phe-Gly-PAB-OH TFA(Synonyms: Mc-GGFG-PAB-OH TFA)

多肽定制(Sar1,Gly8)-Angiotensin II 编码 [51887-62-8]