Lavoltidine(Synonyms: Loxtidine; AH-234844)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Lavoltidine (Synonyms: Loxtidine; AH-234844)

Lavoltidine (Loxtidine) 是一种具有口服活性的,不可逆且高效的组胺 H2 受体拮抗剂。Lavoltidine 强烈抑制胃酸分泌,并诱发高胃泌素血症。

Lavoltidine(Synonyms: Loxtidine;  AH-234844)

Lavoltidine Chemical Structure

CAS No. : 76956-02-0

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia[1].

IC50 & Target

H2 Receptor

 

体内研究
(In Vivo)

Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; for 3 months) shows partial suppression of both gastric acid secretion and progression to neoplasia. Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in H felis-infected INS-GAS mice[1].
Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male hypergastrinemic mice (INS-GAS mice) infected with Helicobacter felis[1]
Dosage: 0.5 g/L
Administration: Orally (drinking water); changed weekly; for 3 months
Result: Showed partial suppression of both gastric acid secretion and progression to neoplasia.

Clinical Trial

分子量

359.47

Formula

C19H29N5O2

CAS 号

76956-02-0

中文名称

拉伏替丁

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Takaishi S, et al. Synergistic inhibitory effects of gastrin and histamine receptor antagonists on Helicobacter-induced gastric cancer.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Lavoltidine(Synonyms: Loxtidine; AH-234844)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Lavoltidine (Synonyms: Loxtidine; AH-234844)

Lavoltidine (Loxtidine) 是一种具有口服活性的,不可逆且高效的组胺 H2 受体拮抗剂。Lavoltidine 强烈抑制胃酸分泌,并诱发高胃泌素血症。

Lavoltidine(Synonyms: Loxtidine;  AH-234844)

Lavoltidine Chemical Structure

CAS No. : 76956-02-0

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia[1].

IC50 & Target

H2 Receptor

 

体内研究
(In Vivo)

Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; for 3 months) shows partial suppression of both gastric acid secretion and progression to neoplasia. Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in H felis-infected INS-GAS mice[1].
Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male hypergastrinemic mice (INS-GAS mice) infected with Helicobacter felis[1]
Dosage: 0.5 g/L
Administration: Orally (drinking water); changed weekly; for 3 months
Result: Showed partial suppression of both gastric acid secretion and progression to neoplasia.

Clinical Trial

分子量

359.47

Formula

C19H29N5O2

CAS 号

76956-02-0

中文名称

拉伏替丁

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Takaishi S, et al. Synergistic inhibitory effects of gastrin and histamine receptor antagonists on Helicobacter-induced gastric cancer.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务