DOTA PEG Maleimide, MW 5000 Cat. No. PG2-DTML-5k 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DOTA PEG Maleimide, MW 5000

Cat. No. PG2-DTML-5k
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Similar names: Maleimide PEG DOTA

Product information:

  • Form: Solid
  • Color: White
  • Solubility: Soluble in water
  • Reactive group: Maleimide
  • Reactive to: Sulfhydryl (-SH)
  • Reactive pH: 6.5-7.5
  • Application: Reactive metal chelator
  • Unit size: 5 mg

Storage:

  • Store at -20 0C. Protect from moisture.

DTPA PEG Maleimide, MW 5000 Cat. No. PG2-DAML-5k 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DTPA PEG Maleimide, MW 5000

Cat. No. PG2-DAML-5k
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Similar names: Maleimide PEG DTPA

Product information:

  • Form: Solid
  • Color: White
  • Solubility: Soluble in water
  • Reactive group: Maleimide
  • Reactive to: Sulfhydryl/thiol (-SH)
  • Reactive pH: 6.5-7.5
  • Application: Reactive metal chelator
  • Unit size: 5 mg

Storage:

  • Store at -20 0C. Protect from moisture.
Related Products
PG2-BNDTA-5k , DTPA PEG Biotin
PG2-DTAFC-5k , DTPA PEG FITC

Folic acid Maleimide Cat. No. FA-ML-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Folic acid Maleimide

Cat. No. FA-ML-1
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Synonym: Maleimide-Folic acid, Folate Maleimide

Product Specification:

  • Appearance: Solid;
  • Color: Yellow;
  • Functional group: Maleimide;
  • Reactive to: Sulfhydryl group;

Storage:

  • Store at -20 0C; 

DSPE Maleimide Cat. No. DS-ML-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DSPE Maleimide

Cat. No. DS-ML-1
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Synonym: Maleimide-DSPE, 1,2-distearoyl-sn-glycerol-phospho-ethanolamine maleimide

Product Specification:

  • Appearance: Solid;
  • Color: white;
  • Lipid type: C18 saturated phospholipid;
  • Functional group: Maleimide;
  • Reactive to: Sulfhydryl group;

Storage:

  • Store at -20 0C; 

Other Products:

DSPE-NHS, DSPE-Biotin, DSPE-PEG, DSPE-FITC, DSPE-Pyrene

DOPE Maleimide Cat. No. DO-ML-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DOPE Maleimide

Cat. No. DO-ML-1
Specification
Unit Size 5 mg
Price $485.00

Qty Add to Cart

Synonym: Maleimide-DOPE, 1,2-dioleoyl-sn-glycerol-phospho-ethanolamine maleimide

Product Specification:

  • Appearance: Solid;
  • Color: white;
  • Lipid type: C18 un-saturated phospholipid;
  • Functional group: Maleimide;
  • Reactive to: Sulfhydryl group;

Storage:

  • Store at -20 0C; 

Other Products:

DOPE-NHS, DOPE-Biotin, DOPE-PEG, DOPE-FITC, DOPE-Pyrene, DOPE-Azide, DOPE-DBCO, DOPE-SPDP

DMG-PEG2000-Maleimide Cat. No. PG2-DGML-2k 50 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

DMG-PEG2000-Maleimide

Cat. No. PG2-DGML-2k
Specification
Unit Size 50 mg
Price $425.00

Qty Add to Cart

Synonym: DMG-PEG2000-Maleimide, DMG PEG Maleimide, MW 2000, Maleimide PEG2000 DMG, 1,2-dimyristoyl-rac-glycero-3-polyethylene glycol 2000

Product Specifications:

  • Form: Solid
  • Color: White
  • Lipid type: DMG (1,2-dimyristoyl-rac-glycerol), C14 saturated
  • Functional tag: Maleimide
  • Reactive to: Sulfhydryl/thiol group
  • PEG type: 2000 PEG, 45 PEG units

Storage:

  • Store at -20 0C. Retest 12 months after receiving.

Biotin-PEG3-maleimide Cat. No. B-P3M-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Biotin-PEG3-maleimide

Cat. No. B-P3M-1
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Description:

Nanocs SnapLink maleimide PEG biotin is a pegylated, thiol/sulfhydryl reactive biotin reagent enables simple and efficient labeling of proteins, antibodies and other macromolecules. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the biotinylated molecules , thus reducing aggregation of labeled substrates in solution. The PEG spacer arm also gives the biotin a long and flexible structure to minimize steric hindrance for binding to streptavidin or avdins. Maleimide reacts efficiently with reduced sulfhydryl groups (-SH) in neutral pH in aqueous buffer to form a stable thiol-ether bond. Nanocs provides a variety of high purity biotin and its derivatives for various biotinylation and bioassay applications. These functional biotin products were purified by chromatography to remove impurities and ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • Appearance (color): White to off-white.
  • Appearance (form): Semi-solid to solid;
  • Solubility: Soluble in DMSO, DMF, water;

Storage Conditions:

  • Store-20 0C, dessiccate. Protect from light.

Biotin-PEG4-maleimide Cat. No. B-P4M-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Biotin-PEG4-maleimide

Cat. No. B-P4M-1
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Description:

Nanocs SnapLink maleimide PEG biotin is a pegylated, thiol/sulfhydryl reactive biotin reagent enables simple and efficient labeling of proteins, antibodies and other macromolecules. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the biotinylated molecules , thus reducing aggregation of labeled substrates in solution. The PEG spacer arm also gives the biotin a long and flexible structure to minimize steric hindrance for binding to streptavidin or avdins. Maleimide reacts efficiently with reduced sulfhydryl groups (-SH) in neutral pH in aqueous buffer to form a stable thiol-ether bond. Nanocs provides a variety of high purity biotin and its derivatives for various biotinylation and bioassay applications. These functional biotin products were purified by chromatography to remove impurities and ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • Appearance (color): White to off-white.
  • Appearance (form): Semi-solid to solid;
  • Solubility: Soluble in DMSO, DMF, water;

Storage Conditions:

  • Store-20 0C, dessiccate. Protect from light.

Biotin-PEG12-maleimide Cat. No. B-P12M-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Biotin-PEG12-maleimide

Cat. No. B-P12M-1
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Description:

Nanocs SnapLink maleimide PEG biotin is a pegylated, thiol/sulfhydryl reactive biotin reagent enables simple and efficient labeling of proteins, antibodies and other macromolecules. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the biotinylated molecules , thus reducing aggregation of labeled substrates in solution. The PEG spacer arm also gives the biotin a long and flexible structure to minimize steric hindrance for binding to streptavidin or avdins. Maleimide reacts efficiently with reduced sulfhydryl groups (-SH) in neutral pH in aqueous buffer to form a stable thiol-ether bond. Nanocs provides a variety of high purity biotin and its derivatives for various biotinylation and bioassay applications. These functional biotin products were purified by chromatography to remove impurities and ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • Appearance (color): White to off-white.
  • Appearance (form): Semi-solid to solid;
  • Solubility: Soluble in DMSO, DMF, water;

Storage Conditions:

  • Store-20 0C, dessiccate. Protect from light.

Biotin-PEG23-maleimide Cat. No. B-P23M-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Biotin-PEG23-maleimide

Cat. No. B-P23M-1
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Description:

Nanocs SnapLink maleimide PEG biotin is a pegylated, thiol/sulfhydryl reactive biotin reagent enables simple and efficient labeling of proteins, antibodies and other macromolecules. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the biotinylated molecules , thus reducing aggregation of labeled substrates in solution. The PEG spacer arm also gives the biotin a long and flexible structure to minimize steric hindrance for binding to streptavidin or avdins. Maleimide reacts efficiently with reduced sulfhydryl groups (-SH) in neutral pH in aqueous buffer to form a stable thiol-ether bond. Nanocs provides a variety of high purity biotin and its derivatives for various biotinylation and bioassay applications. These functional biotin products were purified by chromatography to remove impurities and ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • Appearance (color): White to off-white.
  • Appearance (form): Semi-solid to solid;
  • Solubility: Soluble in DMSO, DMF, water;

Storage Conditions:

  • Store-20 0C, dessiccate. Protect from light.

Biotin-PEG45-maleimide Cat. No. B-P45M-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Biotin-PEG45-maleimide

Cat. No. B-P45M-1
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Description:

Nanocs SnapLink maleimide PEG biotin is a pegylated, thiol/sulfhydryl reactive biotin reagent enables simple and efficient labeling of proteins, antibodies and other macromolecules. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the biotinylated molecules , thus reducing aggregation of labeled substrates in solution. The PEG spacer arm also gives the biotin a long and flexible structure to minimize steric hindrance for binding to streptavidin or avdins. Maleimide reacts efficiently with reduced sulfhydryl groups (-SH) in neutral pH in aqueous buffer to form a stable thiol-ether bond. Nanocs provides a variety of high purity biotin and its derivatives for various biotinylation and bioassay applications. These functional biotin products were purified by chromatography to remove impurities and ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • Appearance (color): White to off-white.
  • Appearance (form): Semi-solid to solid;
  • Solubility: Soluble in DMSO, DMF, water;

Storage Conditions:

  • Store-20 0C, dessiccate. Protect from light.

Biotin-PEG75-maleimide Cat. No. B-P75M-1 5 mg修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Biotin-PEG75-maleimide

Cat. No. B-P75M-1
Specification
Unit Size 5 mg
Price $385.00

Qty Add to Cart

Description:

Nanocs SnapLink maleimide PEG biotin is a pegylated, thiol/sulfhydryl reactive biotin reagent enables simple and efficient labeling of proteins, antibodies and other macromolecules. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the biotinylated molecules , thus reducing aggregation of labeled substrates in solution. The PEG spacer arm also gives the biotin a long and flexible structure to minimize steric hindrance for binding to streptavidin or avdins. Maleimide reacts efficiently with reduced sulfhydryl groups (-SH) in neutral pH in aqueous buffer to form a stable thiol-ether bond. Nanocs provides a variety of high purity biotin and its derivatives for various biotinylation and bioassay applications. These functional biotin products were purified by chromatography to remove impurities and ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • Appearance (color): White to off-white.
  • Appearance (form): Semi-solid to solid;
  • Solubility: Soluble in DMSO, DMF, water;

Storage Conditions:

  • Store-20 0C, dessiccate. Protect from light.

Azido-PEG5-maleimide

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Azido-PEG5-maleimide 

Azido-PEG5-maleimide 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Azido-PEG5-maleimide

Azido-PEG5-maleimide Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Azido-PEG5-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

457.48

Formula

C19H31N5O8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Azido-PEG5-maleimide

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Azido-PEG5-maleimide 

Azido-PEG5-maleimide 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Azido-PEG5-maleimide

Azido-PEG5-maleimide Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Azido-PEG5-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

457.48

Formula

C19H31N5O8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Alkyne-PEG4-maleimide

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Alkyne-PEG4-maleimide 

Alkyne-PEG4-maleimide 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Alkyne-PEG4-maleimide

Alkyne-PEG4-maleimide Chemical Structure

CAS No. : 1609651-90-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

382.41

Formula

C18H26N2O7

CAS 号

1609651-90-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Alkyne-PEG4-maleimide

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Alkyne-PEG4-maleimide 

Alkyne-PEG4-maleimide 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Alkyne-PEG4-maleimide

Alkyne-PEG4-maleimide Chemical Structure

CAS No. : 1609651-90-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

382.41

Formula

C18H26N2O7

CAS 号

1609651-90-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Alkyne-PEG4-maleimide

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Alkyne-PEG4-maleimide 

Alkyne-PEG4-maleimide 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Alkyne-PEG4-maleimide

Alkyne-PEG4-maleimide Chemical Structure

CAS No. : 1609651-90-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

382.41

Formula

C18H26N2O7

CAS 号

1609651-90-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Methyltetrazine-PEG6-maleimide

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Methyltetrazine-PEG6-maleimide 

Methyltetrazine-PEG6-maleimide 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Methyltetrazine-PEG6-maleimide

Methyltetrazine-PEG6-maleimide Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Methyltetrazine-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

687.74

Formula

C32H45N7O10

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Methyltetrazine-PEG6-maleimide

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Methyltetrazine-PEG6-maleimide 

Methyltetrazine-PEG6-maleimide 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Methyltetrazine-PEG6-maleimide

Methyltetrazine-PEG6-maleimide Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Methyltetrazine-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

687.74

Formula

C32H45N7O10

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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Methyltetrazine-PEG6-maleimide

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Methyltetrazine-PEG6-maleimide 

Methyltetrazine-PEG6-maleimide 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Methyltetrazine-PEG6-maleimide

Methyltetrazine-PEG6-maleimide Chemical Structure

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生物活性

Methyltetrazine-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

687.74

Formula

C32H45N7O10

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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