标签归档：maleimidocaproic

6-Maleimidocaproic acid-PFP ester

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

6-Maleimidocaproic acid-PFP ester 

6-Maleimidocaproic acid-PFP ester 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。

6-Maleimidocaproic acid-PFP ester

6-Maleimidocaproic acid-PFP ester Chemical Structure

CAS No. : 692739-25-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

6-Maleimidocaproic acid-PFP ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl-Chain

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

377.26

Formula

C16H12F5NO4
CAS 号

692739-25-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

6-Maleimidocaproic acid-PFP ester

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

6-Maleimidocaproic acid-PFP ester 

6-Maleimidocaproic acid-PFP ester 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。

6-Maleimidocaproic acid-PFP ester

6-Maleimidocaproic acid-PFP ester Chemical Structure

CAS No. : 692739-25-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

6-Maleimidocaproic acid-PFP ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl-Chain

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

377.26

Formula

C16H12F5NO4
CAS 号

692739-25-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

6-Maleimidocaproic acid NHS, EMCS Cat. No. M-C6S-1 50 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

6-Maleimidocaproic acid NHS, EMCS

Cat. No. M-C6S-1 6-Maleimidocaproic acid NHS, EMCS Cat. No. M-C6S-1 50 mg
Specification
Unit Size 50 mg
Price $385.00

Qty Add to Cart

s neutral to basic pH values to proceed. The maleimide group reacts with available –SH groups from naturally occurring or mutagenically derived cysteine residues. Maleimide groups react with sulfhydryl groups at pH 6.5~7.5 at room temperature to form stable thioether bonds.

Physical Properties:

  • Appearance: Off-white/white solid;
  • Purity: >95%
  • Solubility: Soluble in DMF or DMSO; Not soluble in water;

Storage Conditions:

  • Store at -20 0C, Desiccate.

6-Maleimidocaproic acid sulfo-NHS

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

6-Maleimidocaproic acid sulfo-NHS 

6-Maleimidocaproic acid sulfo-NHS 是一种 PROTAC linker，属于 alkyl/ether 类。可用于合成 PROTAC 分子。

6-Maleimidocaproic acid sulfo-NHS

6-Maleimidocaproic acid sulfo-NHS Chemical Structure

CAS No. : 103848-61-9

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

6-Maleimidocaproic acid sulfo-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

388.35

Formula

C14H16N2O9S
CAS 号

103848-61-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

6-Maleimidocaproic acid sulfo-NHS

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

6-Maleimidocaproic acid sulfo-NHS 

6-Maleimidocaproic acid sulfo-NHS 是一种 PROTAC linker，属于 alkyl/ether 类。可用于合成 PROTAC 分子。

6-Maleimidocaproic acid sulfo-NHS

6-Maleimidocaproic acid sulfo-NHS Chemical Structure

CAS No. : 103848-61-9

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

6-Maleimidocaproic acid sulfo-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

388.35

Formula

C14H16N2O9S
CAS 号

103848-61-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

6-Maleimidocaproic acid sulfo-NHS

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

6-Maleimidocaproic acid sulfo-NHS 

6-Maleimidocaproic acid sulfo-NHS 是一种 PROTAC linker，属于 alkyl/ether 类。可用于合成 PROTAC 分子。

6-Maleimidocaproic acid sulfo-NHS

6-Maleimidocaproic acid sulfo-NHS Chemical Structure

CAS No. : 103848-61-9

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

6-Maleimidocaproic acid sulfo-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

388.35

Formula

C14H16N2O9S
CAS 号

103848-61-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

6-maleimidocaproic acid Cat. No. M-6C-1 100 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

6-maleimidocaproic acid

Cat. No. M-6C-1
Specification
Unit Size 100 mg
Price $385.00

Qty Add to Cart

Description:

Nanocs SnapLink maleimide acid is an amine and sulfhydryl reactive crosslinker. This crossliker is non-cleavable and water soluble. It contains a carboxylic acid that can be activated with EDC and reacts toward primary amine groups. The maleimide group reacts with available sulfhydryl groups from naturally occurring or mutagenically derived cysteine residues at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

  • Appearance: Off-white/white solid;
  • Purity: >95%

Storage Conditions:

  • Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.

Maleimidocaproic hydrazide Cat. No. M-C6HZ-1 10 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Maleimidocaproic hydrazide

Cat. No. M-C6HZ-1
Specification
Unit Size 10 mg
Price $385.00

Qty Add to Cart

Description:

Nanocs SnapLink maleimide hydrazide is a heterobifunctional crosslinker. This crosslinker contains a hydrazide group that can be reacted with carbohydrate. The maleimide group reacts with sulfhydryl groups at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

  • Appearance: Off-white/white solid;
  • Purity: >95%

Storage Conditions:

  • Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.